摘要：
目的 探讨我国首例输入性裂谷热危重症病例的救治.方法 对本院收治的我国首例输入性裂谷热危重症病例的临床资料、诊疗经过及预后进行回顾性分析.结果 本例裂谷热危重症患者为45岁男性,在非洲务工两年回国,当地无裂谷热疾病流行.主要临床表现为发热、头痛、周身肌肉酸痛,进行性尿量减少.实验室检查提示肝、肾功能重度损伤.入院第3天,经中国疾病预防控制中心报裂谷热病毒核酸阳性,其他病原核酸均为阴性,确诊为裂谷热.经持续血液净化、保肝、稳定细胞膜以及对症支持治疗后,患者尿量逐渐增加,肝肾功能逐渐恢复正常,痊愈出院.门诊随访半年,肝肾功能均正常,视力无异常.结论 裂谷热作为一种人畜共患病,传入我国的风险逐渐增加.急性肾功能衰竭、急性肝功能损伤是危重症裂谷热的主要表现,经过积极治疗,病情可有效控制.%Objective To investigate the treatment of the first case of rift valley fever in China. Methods The clinical data, treatments, prognosis and follow up data of the first case of rift valley fever in China were analyzed, retrospectively. Results This case of rift valley fever critically ill patient was male, 45 years old, living in Angela for 2 years, there were no rift valley fever epidemic. The main clinical manifestations were fever, headache, abdominal muscle pain, progressive reduction in urine output. Laboratory tests suggested severe liver and kidney function damage. On the third day of admission, the rift valley fever virus was reported positive by the Chinese CDC, and other pathogens were negative and rift valley fever was confirmed. After continuous blood purification, liver protection, stable cell membrane and symptomatic support treatment, the urine output was gradually increased, liver and kidney function gradually recovered. Outpatient follow-up for six months, liver and kidney function of the case were normal, and the patient was discharged. Conclusions As a zoonotic disease, the risk of rift valley fever incoming to China is gradually increased. Acute renal failure and acute liver injury are the main manifestations of critical rift valley fever, it could be effectively controlled after treatment.
