摘要：
Objective To analyze and discuss the clinical value of single photon emission computed tomography(SPECT)/CT fusion imaging in differentiating benign and malignant spinal lesions.Methods From January 2017 to January 2018,70 cases with benign and malignant spinal lesions in Shanxida Hospital were studied.SPECT/CT fusion imaging and SPECT examination were used to compare the diagnosis results between the two groups.Results After SPECT diagnosis,a total of 98 bone metastatic lesions were detected,including 10 false positive lesions,60 benign lesions and 28 false negative lesions.After SPECT/CT fusion imaging,there were 100 lesions,including 4 false positive lesions,59 benign lesions and 37 false negative lesions.In this study,a total of 145 lesions were found in 70 patients with benign and malignant spinal lesions,including 95 benign lesions and 50 malignant lesions.The specificity,sensitivity and accuracy of SPECT/CT fusion imaging [95.79％ (91/95),92.00％ (46/50),93.79％ (136/145)] were higher than those of the control group [82.11％ (78/95),64.00％ (32/50),and 82.76％ (120/145)],the differences were statistically significant (x2 =9.048,11.422,9.578,all P ＜0.05).Conclusion In the diagnosis of benign and malignant spinal diseases,SPECT/CT fusion imaging can accurately distinguish benign and malignant lesions,and clearly reflect the development of the disease,which lay a solid foundation for good treatment in the future.%目的 对单光子发射计算机断层成像(SPECT)/CT融合成像技术在脊柱病变良、恶性鉴别中的应用价值进行分析和讨论.方法 70例研究对象均为山西大医院2017年1月至2018年1月接收的脊柱良性以及恶性病变患者,所选患者分别采用SPECT/CT融合成像和SPECT检查,对两种诊断结果进行对比.结果 经过SPECT诊断之后,总计98处骨转移病灶,其中10处假阳性、60处良性病灶、28处假阴性病灶;经过SPECT/CT融合成像技术之后,总计100处骨转移病灶,其中4处假阳性、59处良性病灶以及37处假阴性病灶;70例脊柱良性以及恶性病变患者中,总计145处病灶,其中95处良性病灶,50处恶性病灶.SPECT/CT融合成像技术特异度、敏感度及准确率分别为95.79％ (91/95)、92.00％ (46/50)、93.79％(136/145),均显著高于对照组的82.11％ (78/95)、64.00％(32/50)、82.76％(120/145),均差异有统计学意义(x2=9.048、11.422、9.578,均P＜0.05).结论 在诊断脊柱良性以及恶性病变的过程中,利用SPECT/CT融合成像可以准确的区分良性以及恶性病变,将患者疾病发展状况清楚的反映出来,为日后良好治疗奠定基础.
