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面神经疾病

面神经疾病的相关文献在1990年到2022年内共计141篇,主要集中在神经病学与精神病学、中国医学、临床医学 等领域,其中期刊论文130篇、会议论文4篇、专利文献109235篇;相关期刊79种,包括河北中医、中国微侵袭神经外科杂志、中华外科杂志等; 相关会议4种,包括中华中医药学会耳鼻咽喉科分会第十二次学术研讨会暨嗓音言语听力医学专题学术研讨会、第三届中国医学美容学术交流研讨会、第五次全国听力学及嗓音言语医学学术交流会等;面神经疾病的相关文献由370位作者贡献,包括樊忠、刘智雄、姜桂凤等。

面神经疾病—发文量

期刊论文>

论文:130 占比:0.12%

会议论文>

论文:4 占比:0.00%

专利文献>

论文:109235 占比:99.88%

总计:109369篇

面神经疾病—发文趋势图

面神经疾病

-研究学者

  • 樊忠
  • 刘智雄
  • 姜桂凤
  • 孟斌
  • 张淞
  • 李军
  • 李敬仁
  • 毕士祥
  • 洪磊
  • 范肖冬
  • 期刊论文
  • 会议论文
  • 专利文献

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    • 李凯庆; 于天洋; 夏雪; 孙远征
    • 摘要: 面肌痉挛主要表现为面部肌肉反复痉挛性抽搐,随着病情的发展,可对患者的日常工作生活造成严重影响。针灸疗法在面肌痉挛治疗方面效果显著,方法众多,具有操作简便、效果可靠、不良反应少等优点。现就几年来有关针灸治疗面肌痉挛的研究进展进行归纳总结,阐述其治疗优势,并分析目前研究存在的问题,以期为临床规范化应用针灸治疗面肌痉挛提供参考。
    • 王晶; 于国渊; 朱旭; 杨华堂; 刘秀杰; 王喜旺; 杨芳
    • 摘要: 目的分析责任血管含椎-基底动脉压迫对面肌痉挛(HFS)病人微血管减压术疗效的影响。方法回顾性分析我院2017年1月—2019年12月收治的102例HFS病人临床资料,根据是否包含椎-基底动脉压迫分为对照组(小动脉压迫)68例、观察组(椎-基底动脉压迫)34例。两组病人均实施微血管减压术治疗。比较两组临床疗效、延迟治愈率、复发率和并发症等指标。结果观察组临床总有效率(76.47%)明显低于对照组(92.65%),对照组治愈病人延迟治愈率(14.89%)明显低于观察组(42.86%),观察组有效病人复发率(19.23%)明显高于对照组(3.17%),观察组并发症发生率(20.59%)明显高于对照组(4.41%),差异均有统计学意义( χ^(2)=3.978~5.003,P<0.05)。结论责任血管含有椎-基底动脉压迫可影响HFS微血管减压术治疗效果,延长治愈时间,增加复发率及并发症发生率。
    • 张维浩
    • 摘要: 面神经麻痹俗称面瘫,急性起病,主要表现为患侧面部表情肌瘫痪,口眼歪斜,额纹消失,不能皱额、蹙眉,眼裂不能闭合或者闭合不全。根据损伤的部位不同分为中枢性面瘫和周围性面瘫,中枢性病变位于面神经核以上至大脑皮层之间的皮质延髓束,通常由脑血管病等引起,可以伴有语言障碍、偏瘫、偏身感觉障碍等症状;周围性面瘫又称面神经炎或贝尔麻痹,是最常见的面神经疾病,大概占面瘫患者的70%以上,可能因茎乳孔内面神经非特异性炎症导致周围性面瘫,一般预后良好。本文探讨的即是周围性面瘫的中医治疗经验。
    • 李丽梅; 张志利; 刘晓东; 徐幼苗; 杨旭; 董蕊; 刘悦
    • 摘要: 目的 探讨CT三维重建下脉冲射频治疗顽固性面肌痉挛的临床效果及其安全性和有效性.方法 回顾性分析2014年12月至2018年12月就诊于秦皇岛市第一医院疼痛科的40例顽固性面肌痉挛患者的临床资料,按照手术方法不同将其分为脉冲射频组和神经阻滞组,每组20例.脉冲射频组采用CT三维重建下脉冲射频术;神经阻滞组先采用超声引导下行茎乳孔区面神经阻滞,每5 d注射1次,共3次,然后超声引导下行星状神经节阻滞,每天阻滞1次,左右交替共10次.记录2组患者术后15 d、3个月、1年时Cohen分级和治愈率,记录术后3个月、1年时复发率及不良反应发生情况.结果 术后15 d,2组患者Cohen分级、治愈率比较,差异无统计学意义(P>0.05).与神经阻滞组比较,脉冲射频组患者术后3个月、1年Cohen分级明显较低,治愈率较高(P<0.05),且无明显不良反应发生.结论 顽固性面肌痉挛患者应用脉冲射频较单纯神经阻滞治疗临床效果更佳,在三维CT影像引导下进行治疗,具有定位精准、安全性高等特点,为面肌痉挛提供了一种安全、可行的治疗方法.
    • 戴群瑶; 洪桂洵; 杨智云
    • 摘要: 目的 探讨微小表面线圈高分辨MR扫描在原发性面神经肿瘤诊断中的临床应用价值.方法 回顾性研究.纳入中山大学附属第一医院耳鼻咽喉科2015年5月-2019年10月经手术或活检病理证实的原发性面神经肿瘤患者16例,其中男11例、女5例,年龄15~56(34.9±11.7)岁.术前均行面部微小表面线圈局部高分辨3 T MR扫描及面神经曲面重建(方法A),同时行常规头线圈MR平扫及增强扫描(方法B).(1)对比分析两种方法成像所显示的肿瘤的位置、累及范围、形态、生长方式以及信号特点的差异,采用配对t检验比较两种方法最大径测量值.(2)以反映肿瘤与面神经关系的特征性的面神经出入征阳性为面神经肿瘤的MRI诊断标准,以病理诊断为金标准,采用配对X2检验比较两种MR扫描方法诊断面神经肿瘤的准确率.结果 (1)两种成像方法显示肿瘤位置、范围、形态一致,但与方法B相比,方法A肿瘤范围的显示更为直观.肿瘤位于左侧9例、右侧7例;所有肿瘤均累及面神经2节段及以上;肿瘤中心位于内听道处1例、迷路段1例、膝状神经节区6例、鼓室内5例、乳突区1例、腮腺区2例;形态表现为7例不规则形、表面分叶状或菜花状,5例呈类圆形,4例呈蘑菇形.(2)方法A测得肿瘤最大径为8~33.5(18.9±7.9)mm,方法B为8.5~32.5(18.8±7.85)mm,两种方法差异无统计学意义(t=0.951,P>0.05).(3)方法A肿瘤信号与面神经信号接近,有囊变者信号不均匀;方法B肿瘤T1 WI以等信号、稍低信号为主,T2 WI呈高信号、稍高信号,有囊变者信号不均匀.(4)本组16例患者采用方法A所得MRI显示面神经出入征均为阳性,方法B仅有4例面神经出入征呈现阳性,诊断准确率分别为16/16和4/16,差异有统计学意义(P =0.000).结论 使用微小表面线圈面神经高分辨MRI结合曲面重建技术可以更加清晰地显示肿瘤与面神经关系,提高原发性面神经肿瘤的诊断准确率;面神经出入征对原发性面神经肿瘤的MRI诊断具有重要价值.
    • 温雪彬; 杨聪娴; 邢倩倩; 赵旭; 麻树霖; 龚顺之; 傅志俭
    • 摘要: Objective To evaluate the efficacy of facial acupoint injection combined with nerve block in treating hemifacial spasm. Methods Fifty?four patients of both sexes, aged 26-73 yr, with the course of disease 6 months-17 yr from February 2015 to January 2016, were included in this study accord?ing to diagnostic criteria for hemifacial spasm based on expert consensus in 2014. Patients were divided into 2 groups(n=27 each)using a random number table: facial acupoint injection combined with nerve block group(group A)and nerve block group(group B). In group A, the mixed injection 2 ml(2% lidocaine hydrochloride 5 ml, compound betamethasone 1 ml, mecobalamin 1 mg, diluted to 18 ml in normal sa?line)was given at facial Sibai, Jiachengjiang, Xiaguan and Yifeng acupoints once every 5 days, 3 times in total;facial nerve block was performed via the stylomastoid foramen with the mixed injection(5 ml) previously described once every 5 days, 3 times in total;stellate ganglion block was performed on the right and left side alternately once a day, 5 times on each side. In group B, patients received facial nerve block and stellate ganglion block, and no facial acupoint injection was applied. The Cohen rating and Shorr out?come were recorded before treatment and at 10th day, 3rd month and 1 yr after treatment, and the recur?rence was recorded at 3 months and 1 yr after treatment. Results Compared with group B, Cohen classifi?cation was significantly decreased, and the effective rate was increased at 10th day, 3rd month and 1 yr af?ter treatment, and the recurrence rate was decreased at 3 months and 1 yr after treatment in group A(P<0.05). Conclusion The facial acupoint injection combined with nerve block produces better long?term ef?ficacy in treating hemifacial spasm than nerve block alone.%目的 评价面部穴位注射联合神经阻滞治疗面肌痉挛的效果.方法 按照2014年面肌痉挛中国专家共识的诊断标准,选取2015年2月至2016年1月面肌痉挛患者54例,年龄26~73岁,性别不限,病程6个月~17年,术后随访1年.采用随机数字表法分为2组(n=27):面部穴位注射联合神经阻滞组(A组)和单纯神经阻滞组(B组).A组行面部四白穴、夹承浆穴、下关穴和翳风穴注射混合药液(2%盐酸利多卡因5 ml、复方倍他米松1 ml、甲钴胺溶液1 mg,生理盐水稀释至18 ml)2 ml,每5 d注射1次,共3次;经茎乳孔行面神经阻滞,药物同上(5 ml),每5 d阻滞1次,共3次;行星状神经节阻滞(1%利多卡因6 ml),每天阻滞1次,左右交替各5次.B组只行经茎乳孔面神经阻滞及星状神经节阻滞,不进行面部穴位注射.于治疗前、治疗后第10天、3个月和1年时记录Cohen分级和Shorr疗效,治疗后3月和1年时观察复发情况.结果 与B组比较,A组患者治疗后第10天、3月和1年时Cohen分级降低,有效率升高,治疗后3月和1年时复发率降低(P<0.05).结论 面部穴位注射联合神经阻滞治疗面肌痉挛的长期疗效优于单纯神经阻滞.
    • 赵芸芸; 高燕军; 董季平; 宁文德; 邬小平
    • 摘要: Objective To explore the application value of contrast-enhanced MRI and curved planar reformation (CPR) in diagnosis of facial neuritis.Methods Contrast-enhanced MRI scans were performed on 30 patients with facial neuritis.The involvement of intracranial facial nerve was observed,and the signal intensity of facial nerve and adjacent temporal lobe was measured with GE AW 4.5 workstation.While the signal intensity ratio (SIR) between facial nerve and adjacent temporal lobe was calculated.CPR of facial nerve was done with Philips EBW workstation,in order to observe the whole course and involvement of facial nerve.Results Among the 30 patients,SIR of affected geniculate ganglion,tympanic segment,labyrinthine segment,internal auditory meatus segment and mastoid segment was 1.59±0.28,1.16±0.16,1.38±0.20,1.30 ±0.19 and 0.96±0.14,respectively.While SIR of the relevant segment in contralateral side was 1.08±±0.19,0.74±0.13,0.81±0.13,0.83±0.08 and 0.69±0.12,respectively.There were significant differences of SIR between the affected and the contralateral segments (all P<0.001).CPR could display the involved location and facilitate visualizing the whole course of facial nerve clearly.Conclusion Contrast-enhanced MRI and CPR are helpful to facilitate visualizing the whole course of facial nerve and clearly reveal the involvement.%目的 探讨MR增强扫描及曲面重建(CPR)在面神经炎诊断中的应用价值.方法 对30例面神经炎患者行MR增强扫描.通过GE AW 4.5工作站观察患者颅内面神经受累情况,测量面神经及邻近颞叶组织的信号强度,计算面神经与同一层面邻近颞叶的信号强度比值(SIR).通过Philips EBW工作站进行面神经的CPR重建,整体观察患者面神经的颅内走行及受累情况.结果 30例面神经炎患者中,患侧面神经膝状神经节、鼓室段、迷路段、内听道段及乳突段的SIR分别为1.59±0.28、1.16±0.16、1.38±0.20、1.30±0.19及0.96±0.14,健侧SIR分别为1.08±0.19、0.74±0.13、0.81±0.13、0.83±0.08及0.69±0.12,各受累部位患侧面神经SIR与健侧差异均有统计学意义(P均<0.001).CPR图像可直观显示面神经受累部位及面神经的颅内走行情况.结论 面神经MR增强扫描及CPR技术有助于清晰显示面神经炎患者颅内面神经走行及受累情况.
    • 杨敏; 唐寅达; 应婷婷; 朱晋; 李世亭
    • 摘要: Objective By simulating the pathology of facial nerve injury for hemifacial spasm, to establish the models of the facial nerve trunk (FNT) local demyelination in SD rats. Methods The local quantitative injury was performed in the intracranial segment of the FNT in SD rats by using quantitative injury tweezers for establishing the animal model of the FNT local demyelination. The function of the facial nerve was evaluated by behavior and neuro-electrophysiological monitoring, and the never injury severity and demyelination severity were identified by pathological examination. Results When using 50 g quantitative injury force, the percentage of degenerated nerve fibers in injury side was about 38.6%, and the latency of F wave in the injury side was more significantly delayed than that in the normal side. Facial nerve was found obvious pathological change of demyelination, while there were no manifestations of facial nerve paralysis. The facial nerve fiber swelling, mild demyelination, and exfoliative myelin sheath after Wallerian degeneration were observed under electron microscope. Conclusions The model of FNT local demyelination in rats can be successfully established by using 50 g quantitative injury force. This animal model is stable, reliable and of good repeatability, which can accurately reflect the characteristics of hemifacial spasm in terms of manifestations, histopathology and electrophysiology.%目的:模拟面肌痉挛面神经损伤病理,制作SD大鼠面神经干局部脱髓鞘模型。方法应用定量损伤镊,对大鼠面神经颅内段主干进行局部定量损伤,制作SD大鼠面神经干局部脱髓鞘模型。通过行为学和神经电生理学检测评估面神经功能,通过病理学检测对面神经损伤程度和脱髓鞘程度进行鉴定。结果使用50 g定量损伤力时,损伤侧变性神经纤维百分数约为38.6%,损伤侧F波潜伏期(Lf)比健侧明显延迟;面神经出现明显脱髓鞘病理改变,而无面神经麻痹表现;电镜观察面神经纤维肿胀、中度脱髓鞘,并有瓦勒变性后脱落的髓鞘。结论应用定量损伤镊,在50 g定量外力作用下,可成功制作大鼠面神经干局部脱髓鞘模型。该模型能够从临床表现、组织学以及电生理学等多方面准确体现面肌痉挛的特点。该模型稳定可靠,可重复性好。
    • 龚继涛; 汤宇
    • 摘要: 目的:探讨中耳胆脂瘤伴面神经受累的临床特点及其情绪变化。方法选取2013年1月至2015年5月于我院耳鼻喉科住院接受治疗的80例中耳胆脂瘤患者为观察组,另选取同时期耳鼻喉科80例非中耳胆脂瘤患者为对照组。统计分析患者面神经骨管缺损部位情况;比较患者缺损部位、恢复时间、面神经功能及焦虑抑郁情绪。结果观察组中神经骨管缺损25例:膝状神经节+水平段1例、水平段17例、垂直段3例、水平段+垂直段4例。术前、术后发生面瘫的患者均有3例,术后发生面瘫均为面神经骨管胆脂瘤破坏,出现不同程度的损伤,面神经暴露且与胆脂瘤及肉芽粘连,术前面瘫比术后面瘫发生时间、恢复时间长,缺损部位无明显差异。观察组面神经功能明显低于对照组,术后6个月观察组患者病情明显改善( P<0.05)。观察组入院前、出院前焦虑情况明显高于对照组(P<0.05),出院前观察组抑郁情况明显高于对照组(P<0.05),出院后6个月2组患者术后焦虑、抑郁情况均明显改善( P<0.05)。结论中耳胆脂瘤伴面神经受累部位多为水平段,术后有发生面瘫风险,术前面瘫比术后面瘫发生时间、恢复时间长,患者焦虑情况、抑郁情况较严重,术后6个月中耳胆脂瘤伴面神经受累患者病情明显改善等临床特点,干预后均有明显改善。%Objective To investigate the clinical characteristics and the emotional changes of middle ear cholesteatoma with facial nerve involvement .Methods The observation group included 80 cases with middle ear cholesteatoma who were admitted into the Department of otorhinolaryngology ,in our hospital from January 2013 to May 2015 .The control group included 80 cases without middle ear cholesteatoma in the same period .We statis‐tically analyzed the defect sites of facial nerve canal ,and compared the defect sites ,recovery time ,facial nerve function and the emotion of anxiety and depression .Results In the observation group ,25 cases were nerve canal defect ,including 1 case of the geniculate ganglion + horizontal section ,17 cases of horizontal section ,3 cases of vertical section and 4 cases of horizontal section + vertical section .There were 3 cases of facial paralysis before the surgery and another 3 cases after the surgery .All the postoperative facial paralysis cases were resulted from bony destruction of facial nerve canal ,which showed a different degree of damage ,the exposure of facial nerve and the adhesion of cholesteatoma and granulation .The occurrence time and recovery time of facial paralysis before the surgery was longer than those after the surgery ;however there was no significant difference for the defect sites . The facial nerve function in the observation group was significantly worse than that of the control group ,and the status of patients in the observation group was significantly improved 6 months after the surgery (P<0 .05) .The anxiety in the observation group was significantly higher than that of the control group either before admission or before discharge from the hospital (P<0 .05) .The depression in the observation group was significantly more ob‐vious than that in control group before admission and discharge from the hospital (P<0 .05) .The anxiety and de‐pression were significantly improved in both observation group and control group 6 months after discharge from hospital (P<0 .05) .Conclusion The most common defect site in middle ear cholesteatoma with facial nerve in‐volvement was horizontal section ,and there was risk for facial paralysis after the surgery .The occurrence time and recovery time of facial paralysis before the surgery was longer than those after the surgery .There were more serious anxiety and depression in patients .The symptoms were significantly improved in middle ear cholesteatoma with facial nerve involvement 6 months after the surgery and all the significant improvements were after interven‐tion .
    • 杰然
    • 摘要: 人物简介 孙连桂:北京伊济源面神经学研究院院长、创始人,现任中国发明协会常务理事,天津市预防医学会第四届理事会常务理事,香港华人华侨总商会名誉会长。孙连桂专注面神经研究20年,先后发表了《面神经研究领域新发现》、《治疗面部神经疾病从激活神经末梢功能开始》、《运用科学管理手段将技术成果“小题大做”》、《浅谈面神经麻痹》、《浅谈面肌痉挛》、《浅谈三叉神经痛》等论文,2013年9月2日,在国际结合医学杂志发表论文《连桂平衡疗法治疗面神经疾病的病例报告》。
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