evaluation

摘要： Background: The Adverse Events following Voluntary Medical Male Circumcision Surveillance System (VMMC AESS) serves to identify adverse events (AEs) for safe provision of VMMC. In 2019, Zvimba District reported two adverse events out of 542 circumcisions translating to a 0.4% AE rate against an acceptable threshold of 2% and this is suggestive of underreporting. We evaluated the system to verify existence of underreporting of AEs, assess the surveillance system attributes and evaluate data quality. Methods: A descriptive cross-sectional study was conducted using the updated Center for Disease Control (CDC) guidelines for surveillance system evaluation. We proportionately sampled VMMC client intake records and purposively selected health workers involved in the VMMC programme into the study. An interviewer-administered questionnaire was used to collect data from 14 - 30 December 2020 on knowledge of the VMMC AESS among health care workers and surveillance system attributes. We used a checklist to check for data quality. Data were analysed using Epi Info 7 statistical software. Results: Of the 31 health workers that participated in the study, 21 (68%) had fair knowledge of the surveillance system. Out of 384 records reviewed, 104 had missing data on AE monitoring days 7 and 42. Sixteen (52%) of participants regarded filling AE reporting forms as difficult and the process as time-consuming. The surveillance system was not representative as only two out of eight facilities were conducting outreaches in hard-to-reach areas. Conclusion: There was possible underreporting of adverse events as about a quarter of reviewed records had missing data on AE monitoring days and the system’s performance was threatened by poor data quality and unavailability of reporting forms. The system was rendered acceptable though unstable, not representative and not simple and the health workers were not making use of the surveillance system. We recommended retraining on the surveillance system for all health care workers involved in VMMC in Zvimba District.

摘要： The objective of this work is to dry the mushrooms to evaluate the impact of drying on them. The drying of mushrooms in the oven, in the solar dryer and in the microwave indicated that for Termitomyces sp. the total polyphenol contents were 15.20 mgEAG/gMs for the microwave drying (280 W), 13.61 mgEAG/gMs for the oven drying (60°C), and 9.81 mgEAG/gMs for the solar dryer drying (40°C). For Pleurotus sp., the contents obtained were 13.79 mgEAG/gMs for microwave drying (280 W), 8.36 mgEAG/gMs for oven drying (60°C) and 8.98 mgEAG/gMs for solar drying (40°C). Regarding flavonoids, for Termitomyces sp., this revealed 0.5797 mgECa/gMs for microwave drying (280 W), 0.729 mgECa/gMs for oven drying (60°C) and 0.5671 mgECa/gMs for solar drying (40°C). The flavonoid contents for Pleurotus sp. gave 0.842 mgECa/gMs for microwave drying (280 W), 1.06 mgECa/gMs for oven drying (60°C) and, 0.425 mgECa/gMs for solar drying (40°C). For Termitomyces sp., the levels of free radical scavenging activity varied from 13.02 mg/mL for microwave drying, 25.08 mg/mL for oven drying, and 22.25 mg/mL for solar drying;while for Pleurotus sp., 15.96 mg/mL for microwave drying, 39.90 mg/mL for oven drying, and 31.60 mg/mL for solar drying.

摘要： BACKGROUND Pancreatic adenocarcinoma is one of the most common malignant tumors of the digestive system.More than 80%of patients with pancreatic adenocarcinoma are not diagnosed until late stage and have distant or local metastases.AIM To investigate the value of computed tomography(CT)perfusion imaging in the evaluation of angiogenesis in pancreatic adenocarcinoma patients.METHODS This is a retrospective cohort study.Patients with pancreatic adenocarcinoma and volunteers without pancreatic diseases underwent CT perfusion imaging from December 2014 to August 2017 in Huashan Hospital,Fudan University Shanghai,China.RESULTS A total number of 35 pancreatic adenocarcinoma patients and 33 volunteers were enrolled.The relative blood flow(r BF),and relative blood volume(r BV)were significantly lower in patients with pancreatic adenocarcinoma than in the control group(P<0.05).Conversely,the relative permeability in patients with pancreatic adenocarcinoma was significantly higher than that in controls(P<0.05).In addition,r BF,r BV,and the vascular maturity index(VMI)were significantly lower in gradeⅢ-Ⅳpancreatic adenocarcinoma than in gradeⅠ-Ⅱpancreatic adenocarcinoma(P<0.05).Vascular endothelial growth factor(VEGF),CD105-MVD,CD34-MVD,and angiogenesis rate(AR)were significantly higher in gradeⅢ-Ⅳpancreatic adenocarcinoma than in gradeⅠ-Ⅱpancreatic adenocarcinoma(P<0.05).Significant correlations between r BF and VEGF,CD105-MVD,AR,and VMI(P<0.01)were observed.Moreover,the levels of r BV were statistically significantly correlated with those of VEGF,CD105-MVD,CD34-MVD,and VMI(P<0.01).CONCLUSION Perfusion CT imaging may be an appropriate approach for quantitative assessment of tumor angiogenesis in pancreatic adenocarcinoma.

摘要： In China,the reform of curriculum evaluation system is the core issue of the reform of higher education.The curriculum evaluation system should focus on students’development needs.Besides,instead of sticking flat,we should create a more multifarious curriculum system for students.

摘要： Introduction:Griseofulvin is an antifungal drug belonging to Biopharmaceutical Classification System(BCS class II)having low solubility.Objectives:To formulate,evaluate and enhance the dissolution of poorly water soluble drug Griseofulvin by using solid dispersion method.Methods:Six formulations were prepared by solid dispersion method using Polyethylene Glycol(PEG 6000)125 mg,0 mg,62.5 mg,100 mg,25 mg,150 mg and superdisintegrants Crospovidone 0 mg,125 mg,62.5 mg,100 mg,25 mg,150 mg in all batches respectively.Findings:Satisfactory results were obtained from evaluation of physical characteristics of Griseofulvin tablets including:carr’s compressibility index(17.5±0.19%to 11.76±0.67%),Hausner ratio(1.21±0.01 to 1.13±0.02)and post compression parameters including:thickness(5.16±0.02 mm to 4.57±0.19 mm),friability(0.024%to 0.322%),hardness(4±0.28 kg/cm^(2)to 5±0.57 kg/cm^(2)),disintegration time(14-870 seconds).Conclusions:F3 was best formulation among all formulated batches with in-vitro drug release 30.05%in 10 minutes,69.21%in 30 minutes and 97.11%in 45 minutes.This indicated that formulation F3 batch with PEG 6000 of 62.5 mg and crospovidone 62.5 mg showed increased dissolution.

摘要： Aim: To describe the socio-demographic profile of the participants and the ocular pathologies seen during a 3-day free eye screening and cataract surgical camp, to identify the groups we need to create awareness to, and to improve access in subsequent outreaches. Method: A retrospective cross-sectional descriptive study was carried out among 552 participants that attended a cataract surgical outreach camp in New Karu Local Government Area (L.G.A.), Nasarawa State from 10th to 14th September 2013. Data were analyzed using SPSS Version 20 using descriptive analysis such as frequencies and cross-tabulation. P Results: Six hundred and sixty-six people registered and 552 were examined comprising of 205 males and 347 females. The majority (81.7%) were younger than 60 years old, accounting for 4.5 times more than those older than 60. Females were in the majority (63%). Amongst those older than 60 years, males were slightly higher as compared to those younger than 60 years, where females were twice as much. Most of the participants (71.3%) reside within the L.G.A. Amongst those that reside within the L.G.A., females were twice the men and there was a fairly even distribution of both sexes amongst those that reside outside the L.G.A. The majority of the screened participants (41%) required presbyopic correction. Cataract was the second commonest ocular pathology (22.6%) and 53 (9.6%) participants with VA ≤ 6/60 were offered the free cataract surgery. Conclusion: There was an increase in female participation and those younger than 60 years. Amongst those younger than 60 years and those that reside within New Karu L.G.A., female participation was twice as much as males. When the barrier of distance is eliminated, it increases female participation.

摘要： BACKGROUND The exact definition of Acute kidney injury(AKI)for patients with traumatic brain injury(TBI)is unknown.AIM To compare the power of the“Risk,Injury,Failure,Loss of kidney function,and End-stage kidney disease”(RIFLE),Acute Kidney Injury Network(AKIN),Creatinine kinetics(CK),and Kidney Disease Improving Global Outcomes(KDIGO)to determine AKI incidence/stage and their association with the inhospital mortality rate of patients with TBI.METHODS This retrospective study collected the data of patients admitted to the intensive care unit for neurotrauma from 2001 to 2012,and 1648 patients were included.The subjects in this study were assessed for the presence and stage of AKI using RIFLE,AKIN,CK,and KDIGO.In addition,the propensity score matching method was used.RESULTS Among the 1648 patients,291(17.7%)had AKI,according to KDIGO.The highest incidence of AKI was found by KDIGO(17.7%),followed by AKIN(17.1%),RIFLE(12.7%),and CK(11.5%)(P=0.97).Concordance between KDIGO and RIFLE/AKIN/CK was 99.3%/99.1%/99.3%for stage 0,36.0%/91.5%/44.5%for stage 1,35.9%/90.6%/11.3%for stage 2,and 47.4%/89.5%/36.8%for stage 3.The in-hospital mortality rates increased with the AKI stage in all four definitions.The severity of AKI by all definitions and stages was not associated with inhospital mortality in the multivariable analyses(all P>0.05).CONCLUSION Differences are seen in AKI diagnosis and in-hospital mortality among the four AKI definitions or stages.This study revealed that KDIGO is the best method to define AKI in patients with TBI.

摘要： Cyclists belong to the group of vulnerable road users and, thus, need particular protection in road traffic. One way to enhance cyclists’ safety is to use urban data (e.g., infrastructure data, accident statistics) to inform cyclists about potentially dangerous areas, allowing them to better adjust to the situation and elevate their self-protection. However, the question is how to inform cyclists about such dangerous areas. In this paper, we present the results of two field studies, investigating two wearables (headphones vs. smart glasses) and different signal options to inform cyclists about dangerous areas. Study participants were cycling along a predefined track and could experience the different wearables and signals. The main aim of the studies was to find out how cyclists perceive and experience the different approaches. Participants’ impressions were captured with questionnaires and interviews. Our results show a clear preference of the headphones over the smart glasses and signaling with intermittent audio while being in the dangerous area. However, we also found that participants’ acceptance of the approach was influenced by the additional perceived benefit the respective wearable would have in daily life. Using a wearable solely to be warned, although this would increase safety, was less acceptable. We discuss the implications of these findings for the design of cyclist warning systems.

摘要： The weight loss of cement slurry is the main cause of early annular air channeling and accurate experimental evaluation of the law of loss change is the key to achieve compression stability and prevent this undesired phenomenon.Typically,tests on the pressure loss of cement slurry are carried out for temperature smaller than 120°C,and this condition cannot simulate effectively the situation occurring in high temperature wells.For this reason,in this study a series of experimental tests have been conducted considering a larger range of temperatures,different retarders and fluid loss additives.The results show that with an increase in the temperature,the weight loss curve of cement slurry changes from a“two-stage”to a“three-stage”behavior,and the risk of channeling increases accordingly.On increasing the amount of retarder and fluid loss additive,the transition time of cement slurry displays a non-monotonic behavior(it decreases first and then increases).It is found that the optimized retarder and fluid loss additive dosage are 0.2%and 2.5%,respectively.

摘要： Aim: This study aims to clarify the current state of advancement of knowledge and skills in the educational process from self-assessments by midwifery student labor and delivery assistance evaluation sheets. Method: Metrology is an observational and retrospective study. Self-assessments in labor and delivery assistance evaluation sheets of midwifery students registered in an advanced midwifery course at Nursing College A from Apr. 2017 to Mar. 2018 were analyzed retrospectively. The end-points were every score of six classifications: health checkups and assessments of women who give birth, preparations for labor and delivery assistance, delivery assistance in the parturient second stage, delivery assistance in the parturient third and fourth stages, midwifery process, and the training manner. Moreover, they also included the scores of 64 evaluation items belonging to any of the six classifications and a comprehensive evaluation score in which students judged the acquisition of all knowledge and skills of delivery assistance. In addition, although not on the evaluation sheet, the average score of all 64 evaluation items was also included. The evaluation criteria were five levels, from one to five. The end-points were examined by comparing the experiences of delivery assistances in two periods of Results: 80 among 91 evaluation sheets from eight out of nine students were analyzed. The average score of all 64 evaluation items, every score of the six classifications, and the comprehensive evaluation score was significantly elevated in the experience periods of 6 ≤ times (P Conclusion: Training in adaptation and enforcement of amniotomy and assistance skills for lacerations sutures will be needed in future educational challenges. Self-assessment scores by midwifery students in labor and delivery assistance evaluation sheets were significantly elevated in the experience periods of 6 ≤ times.

摘要： Customer value is the precondition of triggering the customer to buy；the object of supply chain management is to meet customer needs. Enhancement for customer value based on supply chain should oriented by customer demand, driven healthy exercise of knowledge flow, capital flow and logistics in the entiresupply chain by process management in order to realize the maximization of customer value and enhance thecore competitiveness of enterprises.

摘要： Customer value is the precondition of triggering the customer to buy；the object of supply chain management is to meet customer needs. Enhancement for customer value based on supply chain should oriented by customer demand, driven healthy exercise of knowledge flow, capital flow and logistics in the entiresupply chain by process management in order to realize the maximization of customer value and enhance thecore competitiveness of enterprises.

摘要： Customer value is the precondition of triggering the customer to buy；the object of supply chain management is to meet customer needs. Enhancement for customer value based on supply chain should oriented by customer demand, driven healthy exercise of knowledge flow, capital flow and logistics in the entiresupply chain by process management in order to realize the maximization of customer value and enhance thecore competitiveness of enterprises.

摘要： Customer value is the precondition of triggering the customer to buy；the object of supply chain management is to meet customer needs. Enhancement for customer value based on supply chain should oriented by customer demand, driven healthy exercise of knowledge flow, capital flow and logistics in the entiresupply chain by process management in order to realize the maximization of customer value and enhance thecore competitiveness of enterprises.

摘要： Customer value is the precondition of triggering the customer to buy；the object of supply chain management is to meet customer needs. Enhancement for customer value based on supply chain should oriented by customer demand, driven healthy exercise of knowledge flow, capital flow and logistics in the entiresupply chain by process management in order to realize the maximization of customer value and enhance thecore competitiveness of enterprises.

摘要： The integration of domestic and foreign trade is a form of development compatible with the socialist market economy system of China. In this paper I try to select indicators to measure the level of development of integration of domestic and foreign trade in view of macroeconomic policy environment and micromarket and construct the index system. By the index system the level of integration of domestic and foreigntrade of Henan Province is evaluated and suggestions are offered.

摘要： The integration of domestic and foreign trade is a form of development compatible with the socialist market economy system of China. In this paper I try to select indicators to measure the level of development of integration of domestic and foreign trade in view of macroeconomic policy environment and micromarket and construct the index system. By the index system the level of integration of domestic and foreigntrade of Henan Province is evaluated and suggestions are offered.

摘要： The integration of domestic and foreign trade is a form of development compatible with the socialist market economy system of China. In this paper I try to select indicators to measure the level of development of integration of domestic and foreign trade in view of macroeconomic policy environment and micromarket and construct the index system. By the index system the level of integration of domestic and foreigntrade of Henan Province is evaluated and suggestions are offered.

摘要： The integration of domestic and foreign trade is a form of development compatible with the socialist market economy system of China. In this paper I try to select indicators to measure the level of development of integration of domestic and foreign trade in view of macroeconomic policy environment and micromarket and construct the index system. By the index system the level of integration of domestic and foreigntrade of Henan Province is evaluated and suggestions are offered.