杀虫药,有机磷

摘要： 目的 观察丙氨酰谷氨酰胺注射液治疗重度甲拌磷农药中毒致胃肠功能障碍患者的疗效.方法 将80例符合研究条件的重度甲拌磷农药中毒致胃肠功能障碍患者随机分为对照组(40例)和治疗组(40例).对照组给予禁饮食、阿托品、碘解磷定、抗炎、白蛋白、脂肪乳氨基酸葡萄糖注射液、ω-3鱼油脂肪乳注射液、血液灌流等综合治疗.治疗组在对照组治疗的基础上加用丙氨酰谷氨酰胺注射液.比较两组患者胃肠道功能恢复正常的时间,两组患者胆碱酯酶活力、前白蛋白、白蛋白及总蛋白的变化,解毒药物阿托品及碘解磷定的总用量,以及两组患者入住重症监护室的时间.结果 治疗组患者胃肠功能障碍恢复至正常的时间少于对照组,差异有统计学意义(P＜0.05).给予丙氨酰谷氨酰胺注射液治疗的第3、5、7、10天,治疗组患者的胆碱酯酶活力均明显高于对照组,差异有统计学意义(P＜0.05).给予丙氨酰谷氨酰胺注射液治疗的第5和10天,治疗组患者的前白蛋白、白蛋白及总蛋白均高于同期对照组指标,差异均有统计学意义(P＜0.05).治疗组患者的解毒药物总用量(阿托品、碘解磷定)以及在重症监护室的住院时间均低于对照组,差异有统计学意义(P＜0.05).结论 丙氨酰谷氨酰胺注射液对重度甲拌磷农药中毒致胃肠功能障碍患者有良好的治疗效果.%Objective To observe the therapeutic efficacy of alanyl glutamine injection on patients with gastrointestinal function obstacle caused by severe phorate poisoning.Methods A total of 80 eligible patients with gastrointestinal function obstacle caused by severe phorate poisoning were randomly divided into the control group (n=40) and treatment group (n=40).The control group was treated with the conventional therapy,which included forbidden diet,atropine,pralidoxime iodide,anti-inflammatory,albumin infusion,ω-3 fish oil fat emulsion,protection of organs function,blood perfusion,and Fat Emulsion,Amino Acids (17) and Glucose Injection.The treatment group was treated with alanyl glutamine injection plus the conventional therapy.To observe the time of recovering to normal of gastrointestinal function between the two groups,compared the AChE activity and changes of prealbumin,albumin and total protein of the two groups respectively.Furthermore,the total atropine dosage,the total pralidoxime iodide dosage and ICU stay time between the two groups were also compared.Results The gastrointestinal function recovery time of patients in the treatment group was less than the control group,the difference was statistically significant (P＜0.05).From the third day of treatment,the serum cholinesterase activity of the treatment group was higher than the control group,the difference was statistically significant (P＜0.05).On the 5th day and 10th day of the treatment,the prealbumin,albumin and total protein of the treatment group were significantly higher than these indexes of the control group in the same period,the difference were statistically significant (P＜0.05).The total atropine dosage,the total pralidoxime iodide dosage and ICU stay time in the treatment group were lower than the control group,the difference were statistically significant (P＜0.05).Conclusion Alanyl glutamine injection has a great therapeutic effect for gastrointestinal function obstacle patients caused by severe phorate poisoning.

摘要： Objective To observe the effect of sodium bicarbonate combined with ulinastatin on cholinesterase activity for patients with acute phoxim pesticide poisoning.Methods A total of 67 eligible patients with acute phoxim pesticide poisoning,Who were admitted to the emeryency department of hospital from March 2011 to February 2014,Acording to different treatments au patients were randomly divided into the conventional treatment group (n=34) and the sodium bicarbonate+ulinastatin group (n=35).The conventional treatment group were given thorough gastric lavage with water,the sodium bicarbonate + ulinastatin group were given gastric lavage with 2％ sodium bicarbonate solution.Both groups were given such treatments as catharsis,administration of oxygen,fluid infusion,diuresis,and antidotes such as atropine and pralidoxime methylchloride.On the basis of comprehensive treatment,people in the sodium bicarbonate+ulinastatin group were given 5％ sodium bicarbonate injection and ulinastatin.The clinical effect of the two groups were compared.Results The serum cholinesterase activity of the sodium bicarbonate +ulinastatin group was significantly higher than the conventional treatment group from the 5th day,and the difference was statistically significant(P＜0.05).The total atropine dosage,total pralidoxime methylchloride dosage and hospitalization days were better than the conventional treatment group,and the differences were statistically significant (P＜0.05).The difference in the time of atropinization between the two groups was not statistically significant (P＞0.05).The results of arterial blood pH,HCO3-of the sodium bicarbonate + ulinastatin group were higher than the conventional treatment group,and the difference of HCO3-at the 10th day was statistically significant (P＜0.05).Conclusions Sodium bicarbonate combined with ulinastatin can improve the therapeutic effect and reduce complications in the treatment of acute phoxim pesticide poisoning,and have beneficial effects on the recovery of cholinesterase activity.%目的 观察碳酸氢钠联合乌司他丁治疗急性辛硫磷农药中毒胆碱酯酶活力的影响.方法 2011年3月至2014年2月于我院急诊科病房住院治疗且符合研究条件的急性辛硫磷农药中毒患者69例,按治疗方法不同分为常规治疗组34例,碳酸氢钠+乌司他丁组35例.两组均给予导泻、吸氧、补液、利尿、解毒药物阿托品和氯解磷定等治疗措施.常规治疗组给予清水彻底洗胃,碳酸氢钠+乌司他丁组采用2％碳酸氢钠溶液洗胃.碳酸氢钠+乌司他丁组在综合治疗的基础上,加用5％碳酸氢钠注射液联合乌司他丁治疗,对比两组患者的胆碱酯酶活力的变化.结果 碳酸氢钠+乌司他丁组第5、7、10天及出院时血胆碱酯酶活力明显高于常规治疗组,差异有统计学意义(P＜0.05);碳酸氢钠+乌司他丁组阿托品总用量、氯解磷定总用量、住院时间均低于常规治疗组,差异有统计学意义(P＜0.05);两组阿托品化时间的差异无统计学意义(P＞0.05).碳酸氢钠+乌司他丁组动脉血第10天HCO3-明显高于常规治疗组,差异有统计学意义(P＜0.05).结论 碳酸氢钠联合乌司他丁治疗急性辛硫磷农药中毒,可提高疗效,减少并发症,对胆碱酯酶活力恢复有作用.

摘要： Objective To investigate the value of serum presepsin concentration measurement in the clinical diagnosis and treatment of patients with pesticide poisoning patients.Methods A total of 160 patients with pesticide poisoning were enrolled as study subjects and divided into moderate organophosphate pesticide poisoning group (40 patients),severe organophosphate pesticide poisoning group (40 patients),abamectin pesticide poisoning group (40 patients),and paraquat poisoning group (40 patients).A total of 20 healthy volunteers were enrolled as the control group.All the patients with poisoning received conventional treatment of pesticide poisoning immediately after admission,and serum presepsin concentration was measured on days 1 (within 24 hours after poisoning),3,and 7 of admission,and biochemical and radiological parameters related to the patient' s condition were also examined.The patients with a Presepsin concentration of ＞800 pg/ml on day 1 of admission were randomly divided into conventional treatment group and ulinastatin treatment group,and the treatment outcome was compared between the two groups.Results Compared with the healthy control group,the groups with pesticide poisoning showed significant increases in serum Presepsin concentrations,with the highest degree of increase on day 1 (P ＜0.05).The serum Presepsin concentration was positively correlated with alanine aminotransferase,aspartate aminotransferase,creatine kinase,creatine kinase MB,lactate dehydrogenase,serum creatinine,blood urea nitrogen,interleukin-18,and white blood cell count,but negatively correlated with cholinesterase.In the conventional treatment group and ulinastatin treatment group,the overall response rate was 68％ and 78.8％,respectively,with a significant difference between the two groups (P＜0.05).In 40 patients with paraquat poisoning,32 experienced an increase in serum presepsin concentration,and among these 32 patients,27 (83％) experienced exudation on lung CT.Conclusion Serum Presepsin concentration measurement can assist early diagnosis,evaluation of disease severity,and guidance for clinical medication in patients with pesticide poisoning,especially in those with severe pesticide poisoning and a tendency to multiple organ failure.%目的 研究血清中可溶性CD14亚型(presepsin)SCD14-ST浓度检测对农药中毒患者的临床诊疗意义.方法 选取农药中毒患者160例为研究对象,分为有机磷农药中度中毒组40例,有机磷农药重度中毒组40例,阿维菌素农药中毒组40例,百草枯中毒组40例,以健康志愿者20例为对照组.所有中毒患者放院后即进行农药中毒的常规治疗,并于入院第1天(中毒发生24 h内)、第3天、第7天检测血清中presepsin浓度,以及与病情变化相关的生化指标、影像学等;根据患者入院第1天检测的血清中presepsin浓度选择presepsin大于800 pg/ml的病例,随机分为常规治疗组和乌司他丁治疗组,比较两组治疗效果.结果 与健康对照组比较,各组农药中毒患者的血清中presepsin浓度明显升高,以第1天升高程度最为明显,差异有统计学意义(P＜0.05);血清中presepsin浓度与丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、肌酸激酶(CK)、肌酸激酶同工酶(CKMB)、乳酸脱氢酶(LDH)、血肌酐(SCr)、尿素氮(BUN)、白细胞介素-18(IL-18)、白细胞(WBC)呈正相关;与有机磷农药中毒胆碱酯酶活力呈负相关.血清中presepsin浓度＞800 pg/ml的常规治疗组总有效率为68％,联合乌司他丁治疗组的总有效率为78.8％,两组治疗有效率的差异有统计学意义(P＜0.05).40例百草枯农药中毒患者中,血清中presepsin 浓度明显升高32例,其中27例(83％)肺部CT出现了渗出.结论 检测血清中presepsin浓度对农药中毒患者,尤其是严重的、有进展为多器官功能衰竭趋势的农药中毒患者的早期诊断、病情严重程度评估、指导临床用药均具有潜在意义.

摘要： Objective To analyze the relationship between risk factors and prognosis of acute organophosphorus pesticide poisoning (AOPP).Methods The clinical data including APACHE Ⅱ,D-dimer,Creactive protein,procalcitonin,lactic acid of the 67 cases of acute organophosphorus pesticide poisoning which respectively divided into survival group and death group by the outcome were collected.The independent influcing factors were got by logistic regression analysis.Results The analysis showed that APACHE Ⅱ,Ddimer、C-reactive protein and Procalcitonin were influencing factors to evaluate prognosis of AOPP (P＜0.05).Meanwhile,APACHE Ⅱ and CRP were the independent influencing factors to evaluate prognosis of AOPP(P＜0.05).APACHE Ⅱ 26 分 was the optimum thresholds to acess the prognosis of AOPP and its Youden index was largest.Conclusion APACHE Ⅱ and CRP played an important role in the assessment of prognosis on AOPP.When APACHE Ⅱ was more than 26,it suggested the patient of AOPP will have a bad prognosis.%目的 对影响急性有机磷农药中毒患者预后的危险因素进行分析.方法 选取2010年1月至2015年1月就诊于我院的有机磷农药中毒患者67例,分析患者的APACHEⅡ评分,血D-二聚体(DD2),C反应蛋白(CRP),降钙素原(PCT),乳酸等指标及临床资料,根据患者治疗效果将患者分为存活组53例和死亡组14例,用Logistic回归分析筛选能独立预测患者预后的相关因素.结果 死亡组患者APACHEⅡ,DD2、CRP、PCT明显高于存活组,差异有统计学意义(P＜0.05),其中APACHEⅡ,CRP是影响患者预后的独立危险因素(P＜0.05).APACHE评分26分为评估急性有机磷农药中毒患者预后的最佳临界值.结论 APACHEⅡ评分与CRP在对患者的预后的评估中发挥重要作用,其中APACHEⅡ＞26分提示患者预后较差.

摘要： Objective To find out a method which can assess the prognosis of patients with Acute Organophosphate Poisoning objectively and increase the successful ratio of treatment by investigating relevant factors on the prognosis of the patients with Acute Organophosphate Poisoning.Methods We retrospected 116 patients with Acute Organophosphate Poisoning who were treated in our hospital's emergency room from April 2006 to March 2014.According to the outcome of patients,we distributed the patients to death group and survival group,compared the clinic data and using multivariate analysis with Logistic regression to prognosis factors.Results 116 cases of acute organophosphate poisoning patients died in 23 cases,improved in 93 cases.Death group patients' APACHE-Ⅱ score are higher than whose in the survival group(P＜0.05).Compared with the survival group,patients' body temperature,blood pressure,pH,GCS index were lower in the death group (P＜0.05) and Cr,WBC,ALT,AST,CK-MB,blood glucose,blood lactic acid,heart rate were higher in the death group (P＜0.05),there were significant difference between two groups with statistical.Low blood pressure,lower GCS score,hyperglycemia and high white blood cell count,were independent risk factors of poor prognosis,and hypotension was maximum value of all the factor (OR =54.22).Conclusion APACHE Ⅱ prognostic scoring system can be accurately response,vital signs,white blood cell count,pH,serum creatinine,GCS score and serum sodium value which in this system may be associated with prognosis.To evaluate the severity and prognosis of illness Blood glucose,ALT,AST,CK-MB's rising also has certain value.%目的 探讨急性有机磷中毒(AOPP)患者的预后相关因素,以期寻求客观评价急性有机磷中毒(AOPP)患者预后的方法,提高抢救成功率.方法 回顾性分析自2006年4月至2014年3月我院急诊科收治的116例急性有机磷中毒患者.根据患者治疗结果分死亡组与生存组,对两组患者临床资料,采用logistic回归分析其预后相关因素.结果 116例急性有机磷中毒患者中死亡23例,好转93例.死亡组APACHE-Ⅱ评分高于生存组(P＜0.05).与生存组相比,死亡组患者体温、血压、pH、GCS降低,差异有统计学意义(P＜0.05),血钠、肌酐、白细胞计数、谷氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、肌酸激酶同工酶(CK-MB)、血糖、血乳酸、心率等指标升高,差异有统计学意义(P＜0.05).其中低血压、低GCS评分、高血糖和高白细胞计数是预后不良的独立风险因素,且低血压与预后不良相关性大(OR=54.22).结论 APACHE-Ⅱ评分系统可较准确地反应预后,生命体征、白细胞计数、pH、血肌酐及GCS评分、血钠值可能与预后相关.ALT、AST、CK-MB的升高对评估病情的严重程度及预后也有一定的价值.

摘要： 目的 观察生大黄、蒙脱石散联合序贯性血液净化治疗对重度急性有机磷农药中毒(AOPP)的临床疗效.方法 21例用生大黄、蒙脱石散联合序贯性血液净化治疗的患者为联合治疗组,18例同期收治的因经济困难或家属意愿等原因仅行常规治疗的患者为常规治疗组,均为口服中毒.常规治疗组给予常规治疗,联合治疗组在常规治疗的基础上给予胃管内灌入生大黄、蒙脱石散,同时进行序贯性血液净化治疗.结果 与常规治疗组昏迷至清醒时间[(8.4±2.4)d]机械通气时间[(10.7±2.9)d],住院时间[(16.5±3.7)d]比较,联合治疗组患者昏迷至清醒时间[(6.5±1.3)d]、机械通气时间[(7.9±2.0)d]、住院时间[(13.1±3.2)d]均明显缩短,差异均有统计学意义(P＜0.05).治疗后第5、6、7天,联合治疗组血清中乙酰胆碱酯酶(ChE)活力明显高于常规治疗组,差异有统计学意义(P＜0.05).与常规治疗组比较,联合治疗组阿托品使用总量、使用时间、氯解磷定使用总量、使用时间均明显减少,差异均有统计学意义(P＜0.05).联合治疗组病死率为19.0％(4/21),明显低于常规治疗组的病死率(44.4％,8/18),差异有统计学意义(P＜0.05).结论 生大黄、蒙脱石散联合序贯性血液净化治疗对重度AOPP有较好的治疗效果.%Objective To observe the curative efficacy of rhubard,montmorillonite powder combined with blood purification on treatment for patients with severe acute organophosphorus pesticide poisoning(AOPP).Methods 39 patients with AOPP were divided into treatment group (received the combined treatment of rhubard,montmorillonite powder and blood purification on the basis of routine therapy,n=21) and control group (only received the routine treatment because of financial difficulties or the will of family members,n=18).The differences of clinical manifestations,curative effects and prognosis between two groups were compared.Results The time of consciousness recovery,the duration of mechanical ventilation and the length of stay in hospital in treatment group were (6.5±1.3),(7.9±2.0) and (13.1±3.2) days,which were significantly shorter than those [(8.4±2.4),(10.7±2.9)and (16.5±3.7) days] of control group (P＜0.05).Ⅰ n 5,6 and 7 day after treatment,the cholinesterase (ChE) activities of treatment group were significantly higher than those of control group (P＜0.05).The total amount and using time of atropine and pyraloxime methylchloride in treatment group were significantly smaller and shorter than those in control group(P＜0.05).The death rate of treatment group was [19.0％(4/21 )],which were significantly lower than that of control group [19.0％(4/21 )] (P＜0.05).Conclusion The combined treatment of rhubard,montmorillonite powder and blood purification of the AOPP patients has a better curative effect.

摘要： 目的 采用氧乐果染毒的离体培养心肌细胞模型,观察法舒地尔对染毒心肌细胞的影响及其可能机制.方法 分离雄性SD大鼠心肌细胞,DMEM中常规培养.按培养基中氧乐果及法舒地尔剂量,分为不同剂量组培养,在3、6、12及24 h时,测定各组心肌细胞的存活率,根据各组心肌细胞的存活率,选取中剂量染毒组和中剂量治疗组进行心肌细胞收缩幅度测定,并检测培养基中的乳酸脱氢酶(LDH)活力及心肌细胞Bcl-2和Bax蛋白的表达水平.结果 与正常对照组比较,各染毒组心肌细存活率均明显降低,且随染毒剂量增高,心肌细胞存活率呈降低趋势,差异均有统计学意义(P＜0.01).与正常对照组比较,中剂量染毒组和中剂量治疗组各时点心肌细胞的收缩幅度明显降低,差异有统计学意义(P＜0.01),与中剂量染毒组比较,中剂量治疗组12h及24 h心肌细胞收缩幅度增大,差异有统计学意义(P＜0.01).中剂量染毒组和中剂量治疗组培养基中LDH活力[(224.9±14.7)、(156.0±6.8) U/L]明显高于正常对照组[(59.2±6.5) U/L],中剂量治疗组LDH活力明显低于中剂量染毒组,差异均有统计学意义(P＜0.01).与正常对照组比较,中剂量染毒组和中剂量治疗组Bcl-2蛋白表达明显降低,中剂量染毒组Bax蛋白表达明显增高,差异均有统计学意义(P＜0.01).与中剂量染毒组比较,中剂量治疗组Bcl-2蛋白表达明显增高,Bax蛋白表达明显降低,差异有统计学意义(P＜0.01).结论 法舒地尔能抑制氧乐果诱导凋亡调节蛋白Bax、Bcl-2的异常表达,这可能是其减轻氧乐果对心肌细胞的损害的机制之一.%Objective To investigate the effect of fasudil on in vitro cultured cardiomyocytes (CMs)exposed to omethoate and its possible mechanism.Methods Cardiomyocytes were isolated from male SD rats and were then cultured in DMEM conventionally.The CMs were divided into different groups based on the doses of omethoate and fasudil in culture media.After 3,6,12,and 24 h of culture,the survival rate of CMs in each group was measured,the CMs in the medium-dose omethoate and medium-dose fasudil groups were subject to shortening amplitude measurement,and the content of lactate dehydrogenase (LDH) in culture media and expression of Bcl-2 and Bax in CMs were measured.Results Compared with the normal control group,each omethoate group showed significantly lower survival rate of CMs,which was negatively correlated with the dose of omethoate (P＜0.01).Compared with the normal control group,the medium-dose omethoate and medium-dose fasudil groups showed significantly decreased shortening amplitudes of CMs at all time points (P＜0.01),and the shortening amplitudes of CMs were significantly higher in the medium-dose fasudil group than in the mediumdose omethoate group after 12 h and 24 h of culture (P＜0.01).The LDH level was significantly higher in the mediumdose omethoate and medium-dose fasudil groups than in the normal control group,and the medium-dose fasudil group showed significantly lower LDH level than the medium-dose omethoate group (P＜0.01).Compared with those in the normal control group,the Bcl-2 expression in the medium-dose omethoate and medium-dose fasudil groups was decreased significantly,and the Bax expression in the medium-dose omethoate group was increased significantly (P＜0.01).Compared with the medium-dose omethoate group,the medium-dose fasudil group had significantly increased Bcl-2 expression and significantly decreased Bax expression (P＜0.01).ConclusionFasudil can inhibit the abnormal expression of apoptosis regulatory proteins (Bcl-2 and Bax) induced by omethoate,which might be one of the factors that reduce the toxic effect of omethoate on CMs.

摘要： 目的:探讨血清胆碱酯酶测定在救治急性有机磷农药中毒(AOPP)患者中的作用.方法:回顾性分析AOPP患者293例,根据入院首次血清胆碱酯酶测得值,将纳入患者分为血清胆碱酯酶＜1 000 U/L组和血清胆碱酯酶≥1 000 U/L组.观察2组中毒程度发生率、阿托品过量率、阿托品不足率、机械通气使用率和死亡率.结果:2组轻度中毒、重度中毒发生率比较有显著性差异(P＜0.05),2组呼吸机使用率比较有显著性差异(P＜0.05),2组死亡率比较有显著性差异(P＜0.05).2组轻度中毒、中度中毒、重度中毒时的阿托品化剂量和阿托品维持量各不相同.结论:血清胆碱酯酶活性检测对于判断AOPP患者的中毒程度、疗效、阿托品用量选择以及预后具有指导意义.

摘要： 目的 研究有机磷农药中毒并发迟发性神经病(OPIDN)患者周围神经的F波和A波,在评价有机磷农药中毒的近端神经系统损害中的意义.方法 对24例有机磷农药中毒并发OPIDN的患者进行正中神经、尺神经、胫神经、腓神经的F波和A波的测定,并与正常对照组(30例)进行比较.结果 24例OPIDN中F波异常19例,异常率为79.1%.主要表现为96条神经中有28条神经未引出F波,26条为下肢,2条为上肢.引出的68条神经的F波中有27条出现A波,A波出现率为39.7%,F波引出率为73.8%.30例正常对照组中2例F波中引出A波,F波异常率为6.7%;120条神经F波引出率为100%;F波中引出的A波有4条,A波出现率为3.3%.两组比较,差异均有统计学意义(P<0.05).OPIDN患者各检测神经F波中的F-M间期的平均值、最大值、最小值均明显延长,与对照组比较,差异均有统计学意义(P<0.05).结论 F波和F波中的A波能客观有效地评价OPIDN患者近端神经的运动传导功能,为OPIDN患者的早期诊断提供依据.

摘要： 本申请涉及一种纳米二氧化硅接枝有机功能高分子有机磷杀虫剂缓释剂及其制备方法，并限定所述杀虫剂为三唑磷、毒死蜱、丙溴磷的一种或一种以上任意组合。所述制备方法包括：首先制备空心纳米二氧化硅A，再与氨基硅烷偶联剂制备氨基改性空心纳米二氧化硅B，进而与水、不饱和单体化合物、引发剂、催化剂和表面活性剂制备得到C，再和杀虫剂制备得到杀虫剂纳米缓释剂。本发明的制备方法，成本低，反应条件温和，耗能少，无三废排放；所得产品负载率高，环境相容性好，具有较长的持效期，解决了某些载体中农药突释的问题，减少了施药次数，提高了农药利用率。

摘要： 本发明公开了一种含环氧虫啶和有机磷类杀虫剂的杀虫组合物，有机磷类杀虫剂选自毒死蜱、三唑磷、敌敌畏，环氧虫啶和有机磷类杀虫剂的重量比是1∶60～60∶1。本组合物可配制成农业上允许的水分散粒剂、可湿性粉剂、悬浮剂、可分散油悬浮剂、微囊悬浮剂、乳油或微乳剂剂型，本发明组分合理，杀虫效果好，用药成本低，且其活性和和杀虫效果不是各组分活性的简单叠加，与现有的单一制剂相比，除具有显著的杀虫效果外，而且有显著的增效作用，减缓抗性的产生，制剂残留量少，对作物无污染，安全性好，符合农药制剂的安全性要求，本发明对小麦蚜虫、棉铃虫、黄曲条跳甲、稻纵卷叶螟、稻飞虱等害虫具有较好的防治效果。

摘要： 本发明公开了一种含哌虫啶和有机磷杀虫剂的增效杀虫组合物，该组合物的活性成分由哌虫啶和有机磷杀虫剂组成，所述有机磷杀虫剂为毒死蜱、辛硫磷、三唑磷或丙溴磷，其中哌虫啶与有机磷杀虫剂的重量比为1∶60～10∶1。本发明的组合物可应用于防治鳞翅目或同翅目害虫方面，特别是应用于防治水稻螟虫或飞虱方面，其效果明显高于其单剂使用。它与现有技术相比，能产生较高的协同增效作用，克服和延缓了害虫抗药性，扩大防治谱，杀虫速度快，降低了用药成本，减轻了毒性。

摘要： 本发明公开了一种茶皂素与有机磷类杀虫剂混配的杀虫剂。所述混配农药制剂按重量百分比计，包括0.01～80％的茶皂素、0.5～80％的有机磷类杀虫剂和余量的助剂。所述混配农药制剂可以制备成乳油、可湿性粉剂、微乳剂、悬浮剂、悬浮乳剂或水乳剂。本发明选择有机磷类杀虫剂和茶皂素进行复配，具有显著的增效作用，杀虫活性比单剂明显增强，对多种害虫起到一药兼治的效果，从而减少防治虫害过程中的人力物力投入，提高生产效益，同时在保证药效的前提下明显降低成本，本发明剂型多样，制备方法简单，推广价值很高。

摘要： 本发明涉及一种光降解有机磷类农药杀虫剂的制备方法及由该方法制备的光降解有机磷类农药杀虫剂，该方法包括：a、将粒径为1‑100纳米的二氧化钛粉末分散于水中，得到质量分数为1‑5质量％的悬浮液；b、将步骤a中所得悬浮液在50‑90°C的温度下搅拌1‑5小时后加入粘土、滑石粉、水滑石和氧化铝继续搅拌后过滤并干燥并粉碎，得到光降解剂粉末；c、将步骤b中所得光降解剂粉末焙烧1‑8小时；d、将步骤c中所得光降解剂粉末采用质量分散为丙烯酰胺水溶液进行淋洗；e、将淋洗后的光降解剂粉末在50‑100°C下烘干1‑10小时后分散到机磷类农药中，得到光降解有机磷类农药杀虫剂。本发明方法制备的农药杀虫剂不仅能够杀虫，而且在起效后能够及时地降解，无需进一步的处理。

摘要： 通式I表示的有机磷化合物：式中X

摘要： 本申请涉及一种纳米二氧化硅接枝有机功能高分子有机磷杀虫剂缓释剂及其制备方法，并限定所述杀虫剂为三唑磷、毒死蜱、丙溴磷的一种或一种以上任意组合。所述制备方法包括：首先制备空心纳米二氧化硅A，再与氨基硅烷偶联剂制备氨基改性空心纳米二氧化硅B，进而与水、不饱和单体化合物、引发剂、催化剂和表面活性剂制备得到C，再和杀虫剂制备得到杀虫剂纳米缓释剂。本发明的制备方法，成本低，反应条件温和，耗能少，无三废排放；所得产品负载率高，环境相容性好，具有较长的持效期，解决了某些载体中农药突释的问题，减少了施药次数，提高了农药利用率。

摘要： 本发明属于植物保护领域，涉及农药组合物及其应用领域，具体的说是以蓖麻杀虫物质和常规杀虫剂为组合物，主要用于农作物有害节肢动物的防治。本发明首先公开了一种蓖麻杀虫物质的提取方法，其次公开了一种蓖麻杀虫物质与常规杀虫剂组合物及其应用。本发明乙醇溶液热浸提与超声波浸提组合的方式得到蓖麻杀虫物质，所得蓖麻杀虫物质对多种杀虫剂有显著的增效作用，本发明所述的组合物使用方法简单，便于推广应用，对棉叶螨、斜纹夜蛾、甜菜夜蛾、小菜蛾、蚜虫、粉虱、蓟马和叶螨等多种靶标节肢动物有较好的防效，能在很大程度上降低农药施用量，延缓靶标节肢动物对杀虫剂的抗性发展，符合目前农药减量化和环境友好的要求。

摘要： 本发明公开了一种含环氧虫啶和有机磷类杀虫剂的杀虫组合物，有机磷类杀虫剂选自毒死蜱、三唑磷、敌敌畏，环氧虫啶和有机磷类杀虫剂的重量比是1：60～60：1。本组合物可配制成农业上允许的水分散粒剂、可湿性粉剂、悬浮剂、可分散油悬浮剂、微囊悬浮剂、乳油或微乳剂剂型，本发明组分合理，杀虫效果好，用药成本低，且其活性和和杀虫效果不是各组分活性的简单叠加，与现有的单一制剂相比，除具有显著的杀虫效果外，而且有显著的增效作用，减缓抗性的产生，制剂残留量少，对作物无污染，安全性好，符合农药制剂的安全性要求，本发明对小麦蚜虫、棉铃虫、黄曲条跳甲、稻纵卷叶螟、稻飞虱等害虫具有较好的防治效果。

摘要： 本发明公开了一种茶皂素与有机磷类杀虫剂混配的杀虫剂。所述混配农药制剂按重量百分比计，包括0.01～80％的茶皂素、0.5～80％的有机磷类杀虫剂和余量的助剂。所述混配农药制剂可以制备成乳油、可湿性粉剂、微乳剂、悬浮剂、悬浮乳剂或水乳剂。本发明选择有机磷类杀虫剂和茶皂素进行复配，具有显著的增效作用，杀虫活性比单剂明显增强，对多种害虫起到一药兼治的效果，从而减少防治虫害过程中的人力物力投入，提高生产效益，同时在保证药效的前提下明显降低成本，本发明剂型多样，制备方法简单，推广价值很高。