摘要:
Objective To evaluate the clinical effectiveness of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in single-level lumbar degeneration disease treatment.Methods We retrospectively analyzed the clinical data of 32 patients who underwent the MIS-TLIF surgery from Nov.2013 to Oct.2014 in Shanghai Tongji Hospital.Clinical and radiological outcomes including operation time,X-ray exposure,surgical blood loss,drainage blood loss,complications,visual analogue scores (VAS),Oswestry disability index (ODI) scores,average intervertebral space and fusion rate.VAS scores of low back and leg pain,ODI scores were recorded before and after surgery to evaluate the functional recovery,average intervertebral space height,lumbar and surgical Cobb angle were measured by X-rays before and after surgery to assess recovery of intervertebral space height and the change of lumbar kyphosis.The Bridwell criterion was used for evaluating the interbody fusion and the MacNab criterion was used for assessment after surgery.Results All the patients received successful surgery.The mean operative time was (171.9 ±31.1) min with (36.7 ± 16.4) seconds radiation exposure,and mean blood loss was (153.3 ± 64.8) ml,drainage blood loss was (58.9 ± 49.2) ml.All cases were followed up for (11.6 ± 3.3) months.Compared with preoperation,VAS score of low back and leg pain,ODI score and average intervertebral space showed significant improvements after surgery.There were 26 (81.3%) cases were grade Ⅰ and Ⅱ 3 months after surgery according to the Bridwell criteria while the number was 31 (96.9%) at the last follow-up.The clinical results were excellent in 22 cases,good in 8 cases and fair in 2 cases according to the MacNab criteria at the final follow-up.Conclusion MIS-TLIF under Spodight work channel system is a safe and effective procedure for single segment lumbar degenerative disease and it may offer patients additional advantages in less trauma and reduction of hospital stay.%目的 探讨Spotlight管状微创工作通道下的经椎间孔入路椎间融合(MIS-TLIF)治疗单节段腰椎退变性疾病的临床疗效.方法 回顾性分析2013年11月至2014年10月同济大学附属同济医院脊柱外科32例行Spotlight微创通道下的单节段MIS-TLIF手术资料,记录患者手术时间,术中射线暴露时间,术中出血量,术后引流量.记录患者手术前后腰、腿视觉模拟量表评分(VAS)及Oswestry功能障碍指数(ODI)评分评估患者功能改善情况,测量椎间隙平均高度、腰椎Cobb角和手术节段Cobb角评价椎间孔恢复及腰椎矢状位曲度改变情况,末次随访以Bridwell评价椎间融合情况,以MacNab量表评价临床治疗效果.结果 所有病例均顺利完成手术,手术时间(171.9±31.1) min;术中射线暴露时间为(36.7±16.4)s;术中出血(153.3±64.8) ml,术后引流(58.9±49.2) ml.所有患者均获得随访,随访时间(11.6±3.3)个月,术后2周及末次随访时腰、腿VAS评分及ODI评分较术前明显改善(P<0.01);术前椎间隙高度为(0.98±0.26) cm,术后2周及末次随访为(1.28±0.21) cm和(1.22±0.20) cm,(P<0.01).根据Bridwell椎间融合评价标准,术后3个月Ⅰ级和Ⅱ级为26例,占总数的81.3%,末次随访Ⅰ级和Ⅱ级为31例,占总数的96.9%;根据MacNab量表评价量表,其中优22例,良8例,可2例.结论 Spotlight微创工作通道下的MIS-TLIF治疗单节段腰椎退变性疾病安全、有效,具有创伤小、恢复快的优点.