乳酸钠抑制铜绿假单胞菌生长的机理

摘要

为探索乳酸钠（NaL）抑制铜绿假单胞菌（Pseudomonas aeruginosa）生长的机理,从NaL影响目标菌细胞膜（壁）结构完整性和胞内ATP的合成两方面进行了探讨。研究结果表明,0.02 g/mL NaL显著破坏了细胞膜结构的完整性,对照组破坏程度较小,两者差异显著（P〈0.05）;另一方面,0.02 g/mL NaL抑制了胞内ATP合成,而对照组中ATP含量明显高于NaL试验组（P〈0.05）。试验结果为合理、高效利用乳酸钠为新型肉类防腐剂提供了理论依据。%The antibacterial mechanism of sodium lactate（NaL） to Pseudomonas aeruginosa was studied in this paper.Two aspects were designed as the following： the structural integrity of bacterial cell membrane（wall） and the synthesis of ATP in bacteria.The results showed that the structural integrity of bacterial cell membrane was much more significantly destroyed by 0.02 g/mL NaL than control（P0.05）.Meanwhile,ATP product of the treatment with 2 g/100mL NaL was less than that of the control.The conclusion of experiment provides some theoretical references for using NaL as right and effective new food preservatives.