首页> 中文期刊> 《中国循证心血管医学杂志》 >良性前列腺增生症人群中糖尿病与高血压关系的病例-对照研究

良性前列腺增生症人群中糖尿病与高血压关系的病例-对照研究

     

摘要

目的 探讨良性前列腺增生症人群中糖尿病与高血压的相关性.方法 从BPSC研究中初筛良性前列腺增生症患者435例.纳入报告有血压、体重、身高、前列腺体积、空腹血糖和生物学特征等指标的受试者.将符合条件的受试者分为高血压与非高血压组.采用SPSS 19.0软件采用单因素和多因素logistic回归分析进行评估.结果 最终共纳入327例,其中高血压患者108例,非高血压患者219例.结果表明,在所有良性前列腺增生症患者中,糖尿病可使高血压发病的风险增加1.24倍(OR=1.24,95%CI:0.58~2.65),经校正后提高到1.85倍(95%CI:0.51~6.74).在轻度、中度和重度高血压患者中也有相似的研究结果(P均>0.05).结论 研究表明良性前列腺增生症患者糖尿病与高血压间很可能存在正相关,但无统计学差异.%Objective To investigate whether diabetes mellitus was correlated with hypertension in benign prostatic hyperplasia patients. Methods A total of 435 benign prostatic hyperplasia patients were included from the BPSC database for further selection. We included the patients if the relevant data of blood pressure, height, weight, prostate volume, fasting blood sugar, and biological parameters were recorded. Participants were divided into two groups by with hypertension or not. The univariate and multivariate logistic regression analyses were used to assess the data through SPSS 19.0 software. Results Finally 327 patients involving 108 hypertensive patients and 219 non-hypertensive patients were included in present study. The results showed that diabetes mellitus increased the risk of hypertension by 1.24 times in all benign prostatic hyperplasia patients (OR=1.24, 95%CI:0.58~2.65), which was elevated to 1.85 times after adjustment (95%CI:0.51~6.74). The similar results were also observed in mild, moderate, and serious hypertensive patients, respectively (all P>0.05). Conclusion The present study suggests a positive but non-significant correlation between diabetes mellitus and hypertension in benign prostatic hyperplasia patients.

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