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口服抗高血压药

口服抗高血压药的相关文献在2004年到2022年内共计55篇,主要集中在药学、内科学、工业经济 等领域,其中期刊论文54篇、会议论文1篇、专利文献262416篇;相关期刊26种,包括佛山科学技术学院学报(自然科学版)、保健医学研究与实践、中国保健营养(中旬刊)等; 相关会议1种,包括中国药学会第十三届青年药学科研成果交流会等;口服抗高血压药的相关文献由128位作者贡献,包括张桂芬、张桂云、朱爱国等。

口服抗高血压药—发文量

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论文:54 占比:0.02%

会议论文>

论文:1 占比:0.00%

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论文:262416 占比:99.98%

总计:262471篇

口服抗高血压药—发文趋势图

口服抗高血压药

-研究学者

  • 张桂芬
  • 张桂云
  • 朱爱国
  • 李建红
  • 王冬
  • 王建
  • 王斌
  • 王莉文
  • 田德蔷
  • Jin Di
  • 期刊论文
  • 会议论文
  • 专利文献

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    • 黄晓威; 沈云珠; 傅新阳; 洪珊珊; 林志航
    • 摘要: 目的促进口服抗高血压药的合理使用。方法采用限定日剂量(DDD)法,回顾性分析福建医科大学附属泉州第一医院2016年至2020年口服抗高血压药的销售金额、用药频度(DDDs)及限定日费用(DDDc)等指标,总结该类药物的应用情况并评价其合理性。结果2016年至2020年,该院口服抗高血压药的DDDs由586.86万增至976.89万,年均增幅13.73%;销售金额由1866.36万元至2975.42万元,年均增幅12.78%;DDC先由3.18元(2016年)升至3.32元(2018年),后降至3.05元(2020年)。常用的抗高血压药类别为钙通道阻滞剂(CCB)、血管紧张素Ⅱ受体阻滞剂(ARB)、血管紧张素转换酶抑制剂、复方制剂,5年间CCB的DDDs构成比从25.93%增至32.86%,而ARB的DDDs构成比从24.69%降至20.23%,但均稳居前2位。5年间单药的平均DDDc由3.63元降至3.50元,但每年DDDs排序前10位的单药多为进口或合资品种,其DDDc普遍较高。2018年DDDs排序前列的氯沙坦钾片等药品,到2020年已被国家集采药品取代并被挤出前10。结论该院口服抗高血压药的应用基本合理,但临床更倾向于优先选择DDDc较高的进口或合资品种,不利于改善患者的用药依从性。未来临床应优先考虑选择应用方便、质优价廉的药品。
    • 樊鑫
    • 摘要: 目的:了解河南中医药大学第一附属医院(以下简称"我院")门诊药房口服抗高血压药应用情况,为临床合理用药提供依据.方法:采用金额排序和限定日剂量分析方法,对2013—2016年我院门诊药房口服抗高血压药的品种、销售金额、用药频度和限定日费用等进行统计分析.结果:2013—2016年我院门诊药房口服抗高血压药的销售金额总体呈增长趋势,其中钙通道阻滞剂(calcium channel blocker,CCB)、血管紧张素Ⅱ受体阻断剂(angiotensinⅡreceptor blocker,ARB)的销售金额排序居前2位,且其销售金额占比均>30%;DDDs排序无变化,由高至低依次为CCB、ARB、血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、复方制剂、β受体阻断剂和利尿剂,其中,CCB、ARB和ACEI的DDDs合计占比>80%.结论:我院门诊药房口服抗高血压药的销售金额和DDDs总体呈增长趋势,临床多优先选择CCB、ARB和ACEI,并倾向选择长效制剂,而固定的复方制剂尚未得到广泛应用.%OBJECTIVE: To investigate the application of oral antihypertensive agents in outpatient pharmacy of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine ( hereinafter referred to as "our hospital") , so as to provide references for clinical rational drug application .METHODS:Amount ranking and defined daily dose (DDDs) were adopted to analyze the categories, consumption sums, DDDs and defined daily cost (DDC) of oral antihypertensive agents in outpatient pharmacy in our hospital during 2013-2016.RESULTS:The consumption sum of oral antihypertensive agents in outpatient pharmacy in our hospital during 2013-2016 was in an increasing trend, of the consumption sums of calcium channel blocker ( CCB ) and angiotensin Ⅱ receptor blocker ( ARB ) ranked the top 2 , both accounted for over 30% of the total consumption sum; the sequence of DDDs remained from high to low were respectively CCB, ARB, angiotensin converting enzyme inhibitor (ACEI), compound preparations,β-receptor blocking and hydragogue , the DDDs of CCB , ARB and ACEI accounted for over 80% of the total DDDs. CONCLUSIONS: The consumption sum and DDDs of oral antihypertensive agents in outpatient pharmacy in our hospital were in an overall increasing trend , CCB , ARB and ACEI are more prior in clinics , long-time preparations are more tend to be chosen , however , fixed compound preparations are not widely applied yet .
    • 王天宇; 窦倩; 郭子坤
    • 摘要: 目的:了解中国人民武装警察部队学院医院(以下简称"我院")门诊抗高血压药使用情况,为合理用药和药品管理提供参考.方法:按照限定日剂量法,对2015—2017年我院门诊口服抗高血压药的销售金额、用药频度(defined daily dose system,DDDs)及限定日费用(defined daily cost,DDC)等进行统计分析;收集同期门诊口服抗高血压药处方3072张,对抗高血压药联合应用情况进行分析.结果:2015—2017年我院口服抗高血压药销售金额合计498628.57元;销售金额排序及DDDs排序均居首位的抗高血压药类别为钙通道阻断剂;销售金额排序居前3位的药品依次为苯磺酸左旋氨氯地平片、氯沙坦钾片和苯磺酸氨氯地平片;DDDs排序居前3位的药品依次为苯磺酸左旋氨氯地平片、酒石酸美托洛尔片和马来酸依那普利片;抗高血压药联合应用处方少于单独用药处方,且有少数非相关指南常规推荐的联合用药方案.结论:我院门诊口服抗高血压药的应用基本合理,但联合用药处方所占比例较低,且部分联合用药方案需要进一步规范.
    • 王冬; 张桂云; 李建红
    • 摘要: 目的 了解某医院(以下简称"该院")门诊药房口服抗高血压药应用情况,为临床合理用药提供参考.方法 采用金额排序和限定日剂量分析方法,对2016年该院门诊药房口服抗高血压药的品种、销售金额、用药频度和限定日费用等进行统计分析.结果 2016年该门诊药房口服抗高血压药的销售总金额为476.88万元,其中钙通道阻滞剂(calcium channel blocker,CCB)、复合制剂(ARB与利尿剂)的销售金额排序居前两位,且其销售金额占比分别为39.10%、24.25%;用药频度前2位的CCB(苯磺酸氨氯地平)和复方制剂(厄贝沙坦氢氯噻嗪片).结论 该院门诊药房口服抗高血压药使用基本合理,临床多优先选择CCB、复方制剂和ARB,并倾向选择长效制剂.
    • 徐振亚; 刘英; 张桂芬
    • 摘要: 目的:了解常熟市第二人民医院(以下简称"我院")抗高血压药的使用情况,为临床合理用药及药品管理提供依据.方法:按照世界卫生组织推荐的限定日剂量法,对2014-2016年我院口服抗高血压药的销售金额、年增长率、构成比,用药频度(defined daily dose system,DDDs)及限定日费用(defined daily cost,DDC)等指标进行回顾性统计分析.结果:2014-2016年我院口服抗高血压药销售金额分别为1 562.44、1 593.24和1 617.60万元,西药销售金额分别为32 010.38、31 162.36、31 218.22万元,口服抗高血压药销售金额占西药销售金额的比例分别为4.88%、5.11%和5.18%;2015年我院口服抗高血压药销售金额较2014年增长了1.97%,2016年较2015年增长了1.53%;3年来,销售金额和DDDs排序均居第1、2位的抗高血压药类别分别为血管紧张素Ⅱ受体拮抗剂和钙通道阻滞剂.3年来,销售金额排序居前3位的单品种抗高血压药依次为缬沙坦胶囊(合资)、厄贝沙坦片(进口)和氨氯地平片(合资),销售金额排序居前15位药品的销售金额累计占口服抗高血压药销售金额的90.81%;3年来,DDDs排序居前3位的单品种抗高血压药依次为美托洛尔缓释片(进口)、氨氯地平片(国产)和左旋氨氯地平片(国产),DDDs排序居前15位药品的DDDs累计占口服抗高血压药DDDs的86.97%.结论:我院口服抗高血压药的使用与《中国高血压防治指南(2010年版)》的推荐基本一致,符合目前抗高血压药的使用规律和趋势.不足之处在于对复方抗高血压药的选择倾向于相对较低.%OBJECTIVE:To investigate the application of oral antihypertensive drugs in Changshu the Second People's Hospital(hereinafter referred to as "our hospital"), so as to provide references for the rational application and management of the drugs.METHODS: According to the defined daily dose recommended by the WHO, the application of oral antihypertensive drugs in our hospital during 2014-2016 was retrospectively analyzed in terms of consumption sum, annual growth rate, constituent ratio, defined daily dose system(DDDs)and defined daily cost (DDC), etc.RESULTS: The consumption sum of oral antihypertensive drugs during 2014 to 2016 were respectively 15.624 4 million yuan, 15.932 4 million yuan, 16.176 0 million yuan, and the consumption sum of western medicine were respectively 320.103 8 million yuan, 311.623 6 million yuan, 312.182 2 million yuan, which accounted for respectively 4.88%, 5.11% and 5.18% of the consumption sum of western medicine.The consumption sum of oral antihypertensive drugs in 2015 increased by 1.97% over in 2014, and that in 2016 increased by 1.53% over in 2015.Among the 3 years, the angiotensin Ⅱ receptor blocking agents (ARB) and calcium-channel blockers (CCB) ranked top 2 both in the consumption sum and the DDDs, and the top 3 single antihypertensive drugs ranked by consumption sum were respectively valsartan capsules (joint venture), irbesartan tablets (imported) and amlodipine tablets (joint venture), the consumption sum of top 15 drugs accounted for 90.81% of the total amout of oral antihypertensive drugs.The top 3 single antihypertensive drugs ranked by DDDs were respectively metoprolol sustained-release tablets(imported), amlodipine tablets(domestic)and levamlodipine tablets (domestic), the DDDs of top 15 drugs accounted for 86.97% of the total amount of oral antihypertensive drugs.CONCLUSIONS: The application of oral antihypertensive drugs in our hospital is basically consistent with the Guideline for Prevention and Control of Hypertension in China(2010), in accord with the application regularity and trend of oral antihypertensive drugs.However, the application of compound antihypertensive drugs was relatively low.
    • 支文煜; 张桂芬; 朱爱国
    • 摘要: 目的:了解常熟市4家重点医院口服抗高血压药的使用情况,为临床合理用药及药品管理提供依据.方法:对2014—2016年4家医院口服抗高血压药的销售金额、用药频度、限定日费用等进行回顾性统计分析.结果:2014—2016年4家医院口服抗高血压药的销售金额分别为3031.60、3297.77、3325.36万元,2015年较2014年增长8.78%、2016年较2015年增长0.84%,3年销售金额合计占西药总销售金额的比例为3.85%(9654.73万元/250928.09万元)、占心血管系统用药销售金额的比例为46.20%(9654.73万元/20898.86万元);销售金额排序、DDDs排序居第1、2位的为血管紧张素Ⅱ受体阻断剂、钙通道阻滞剂;销售金额排序居前3位的品种为厄贝沙坦、缬沙坦和氨氯地平;DDDs排序居前3位的品种为氨氯地平、厄贝沙坦和左旋氨氯地平;血管紧张素Ⅱ受体阻断剂复方制剂的销售金额和DDDs的年均增长率分别为30.89%和17.17%.结论:常熟市4家医院口服抗高血压药的使用与《中国高血压防治指南(2010年版)》的推荐基本一致,符合目前抗高血压药的使用规律和趋势.%OBJECTIVE:To investigate the application status of oral antihypertensive drugs in four key hospitals in changshu, so as to provide basis for the rational application and management of the drugs. METHODS: Statistically retrospective analysis was conducted on the application data of consumption sum, defined daily dose system( DDDs) and defined daily cost( DDC) , etc. RESULTS:The consumption sum of oral antihypertensive drugs were respectively 30. 3160, 32. 9777 and 33. 2536 million yuan, compared with 2014, the increasing rate in 2015 was 8. 78%;compared with 2015 , the increasing rate in 2016 was 0. 84%. The ratio of consumption sum of three years to the total consumption sum of western medicine was 3. 85%( 96. 5473 million yuan/2509. 2809 million yuan ); the ratio of consumption sum of three years to consumption sum of drugs for cardiovascular diseases was 46. 20%(96. 5473 million yuan/208. 9886 million yuan ) . The top two drugs ranked by consumption sum and DDDs were respectively angiotensinⅡreceptor blocking agents ( ARB ) and calcium-channel blockers ( CCB ) . The top three drugs ranked by consumption sum were respectively irbesartan, valsartan and amlodipine. The top three drugs ranked by DDDs were respectively amlodipine, irbesartan and levamlodipine. The annual increasing rate of consumption sum and DDDs were respectively 30. 89% and 17. 17%. CONCLUSIONS: The application of oral antihypertensive drugs in four key hospitals is basically consistent with Guidelines for Prevention and Treatment of Hypertension in China(2010 Edition) , in accordance with the current antihypertensive medication rule and the trend of drug application.
    • 窦中伟; 王清理
    • 摘要: 目的:了解县区公立医疗机构口服抗高血压药使用情况.方法:采用回顾性分析方法,统计2015年漯河市全部县区5家公立医疗机构口服抗高血压药的种类、使用量、销售金额、用药频度及限定日费用等,分析其可获得性及可负担性.结果:《国家基本药物目录》(2012版)中口服抗高血压药共10个品种,14个品规,其中8个品规在漯河市5家县区公立医疗机构中具有较好的获得性(≥80%),分别为卡托普利片(25 mg)、依那普利片(10 mg)、缬沙坦胶囊(原研药,80 mg)、硝苯地平片(10 mg)、硝苯地平缓释片(20 mg)、硝苯地平控释片(原研药,30 mg)、吲达帕胺片(2.5 mg)和氨氯地平片(国产仿制药+原研药,5 mg);尼群地平、硝苯地平和卡托普利等国产药较原研药有较好的可负担性;硝苯地平缓释片、氨氯地平片和卡托普利片的用药频度排序居前列.结论:医学专业指南对药物选择具有较强的指导意义;在面对基层患者时,药物的可负担性影响医师的药物选择;应继续完善基本药物制度,改善基本药物的可负担性,保证基层患者口服抗高血压药的使用更安全、有效.%OBJECTIVE:To investigate the application status of oral antihypertensive drugs in county public medical institutions .METHODS:By retrospective analysis method , statistical analysis was conducted on application data of oral antihypertensive drugs in 5 county public medical institutions of Luohe in 2015 , in terms of categories , consumption amount, consumption sum, defined daily dose system(DDDs) and defined daily cost(DDC), etc.The availability and affordability were analyzed .RESULTS:According to National Essential Medicine List (2012 Edition), there were 10 categories and 14 productrules , among which 8 productrules had good availability (≥80%) in 5 county public medical institutions , respectively , Captopril tablets ( 25 mg ) , Enalapril tablets ( 10 mg ) , Valsartan capsules ( original drug , 80 mg ) , Nifedipine tablets ( 10 mg ) , Nifedipine delayde-release tablets ( 20 mg ) , Nifedipine controlled release tablets ( original drug , 30 mg ) , Indapamide tablets ( 2.5 mg ) and Amlodipine tablets ( homebred generics+original drug, 5 mg).Compared with original drugs , domestic drugs as niqidan , nifedipine, captopril had better affordability .DDDs of Nifedipine tablets , Amlodipine tablets and Captopril tablets took the lead .ONCLUSIONS:Medical professional guide has strong guiding significance for drug selection .The affordability of drugs affect the drug selection of clinicians .It is necessary to improve essential medicine institution , improve the affordability of drugs and ensure safe and effective application of oral antihypertensive drugs for patients .
    • 王斌; 郑英丽
    • 摘要: Objective:To analyze and discuss the use of oral antihypertensive drugs in the inpatients of a hospital in Beijing,and to provide reasonable reference for clinical use of oral antihypertensive drugs.Methods:To analyze the types,dosage,frequency and daily cost of oral antihypertensive drugs in 2014 ~ 2015 by retrospective method.Results:Most of the oral antihypertensive drug DDDs showed an increasing trend year by year,DDC decreased year by year.CCB and angiotensin Ⅱ receptor antagonists were the first-line therapies for hypertension in the hospital.Conclusion:The use of oral antihypertensive drugs in the hospital during 2014 ~ 2015 was in accord with the trend of clinical drug use.%目的:对北京某三甲医院(简称某院)住院患者口服抗高血压药使用情况进行分析、讨论,研究其使用特点,以期为临床使用口服抗高血压药提供合理参考.方法:采用回顾性方法对2014 ~2015年口服抗高血压药的种类、用量、用药频度、日均费用等进行分析.结果:该院大部分口服抗高血压药DDDs呈逐年上升趋势、DDC逐年下降,钙通道阻滞剂和血管紧张素Ⅱ受体拮抗剂作为该院临床治疗高血压的一线用药.结论:该院2014-2015年口服抗高血压药使用情况基本符合临床用药趋势.
    • 沈达; 王建; 张桂芬
    • 摘要: 目的:为合理使用及管理口服抗高血压药提供参考.方法:采用回顾性方法,按世界卫生组织推荐的限定日剂量进行计算,对我院2011-2013年使用的口服抗高血压药的总用药金额、用药频度(DDDs)和日均费用(DDC)等指标进行分析和评价.结果:2011-2013年采购金额和DDDs均处于第1、2住的药物是血管紧张素Ⅱ受体阻滞药(ARB)和钙通道阻滞药(CCB);3年中,单品种采购金额排序列前3位的依次为厄贝沙坦片(进口)、缬沙坦胶囊(合资)和厄贝沙坦氢氯噻嗪片(合资),采购金额排序前10位药品累计占全部的85.30%;DDDs排序列前3位的药品依次为厄贝沙坦氢氯噻嗪片(合资)、美托洛尔缓释片(进口)和厄贝沙坦片(进口),DDDs排序前10位药品累计占全部的75.25%.结论:我院口服抗高血压药使用与《中国高血压防治指南》(2010年版)推荐的基本一致,符合目前抗高血压药的用药规律和用药趋势.但选择用药时,既要考虑安全性和有效性,还要兼顾经济性,优先使用基本药物,以减轻患者经济负担,确保医药卫生资源的有效利用.
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