Reactions of Ethyl 1-Benzyliclene-7a-hydroxy-4-phenyl-6-oxo-octahydro-1H-indene-5-carboxylate and Ethyl 5-Benzylidene-4a-hydroxy-1-pheeyl-3-oxodecahydronaphthalene-2-carboxylate with 2,2,4-Triazol-3-amine. Synthesis of Substituted Triazoloquinazolines

摘要

Due to the presence of several reaction centers, hydroxy oxo derivatives of octahydroindene and deca-hydronaphthalene may be used as intermediate products in the synthesis of various complex systems. The 1,3-dicarbonyl fragment in their molecules is capable of being involved in heterocyclizations with difunc-tional nucleophiles. Reactions of such compounds with hydrazine and hydroxylamine were studied in sufficient detail [1]. However, only a few data are available on reactions of their analogs, hydroxyoxocyclo-hexanecarboxylates, with 3-amino-1,2,4-triazole [2]; the product structure was thoroughly studied using 2D NMR spectroscopy.