Angiotensin converting enzyme inhibitory activity in peptic hydrolysates of cooking discards from anchovy factory ship

摘要

The angiotensin converting enzyme (ACE) inhibitory activity in peptic hydrolysate of raw anchovy cooking discards was 51.3 percent at 1 mg of protein per 100 #mu#L sample solution. While, after the treatment of pepsin for 4 h, was 65.8 percent. The crude peptides fractionated through Bio-gel P-2 column chromatography consisted of five fractions (P-1-P-5) and had maximum inhibitory activity in the fraction P-2 (IC_(50)=0.319 mg protein/mL). The fraction P-2 was rich in aspartic acid, glutamic acid, and glycine.