Tularemia vaccine: Safety, reactogenicity, 'Take' skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial

Mulligan Mark J.; Stapleton Jack T.; Keitel Wendy A.; Frey Sharon E.; Chen Wilbur H.; Rouphael Nadine; Edupuganti Srilatha; Beck Allison; Winokur Patricia L.; El Sahly Hana M.; Patel Shital M.; Atmar Robert L.; Graham Irene; Anderson Edwin; El-Kamary Samer S.; Pasetti Marcela F.; Sztein Marcelo B.; Hill Heather; Goll Johannes B.

首页> 外文期刊>The American Naturalist: Devoted to the Conceptual Unification of the Biological Sciences >Tularemia vaccine: Safety, reactogenicity, 'Take' skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial

【24h】

Tularemia vaccine: Safety, reactogenicity, 'Take' skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial

机译：Tularemia疫苗：安全性，反应源性，“服用”皮肤反应，并在疫苗接种后的抗体反应与新的很多Francisella Tularentsis活疫苗菌株 - A相随机临床试验

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: Tularemia is caused by Francisella tularensis, a gram-negative bacterium that has been weaponized as an,aerosol. For protection of personnel conducting biodefense research, the United States Army required clinical evaluation of a new lot of tularemia live vaccine strain manufactured in accordance with Current Good Manufacturing Practices.

机译：背景：Tularemia是由Francisella Tularensis引起的，这是一种被武器化的革兰氏阴性细菌作为气溶胶。为了保护生物义研究的人员，美国陆军需要按照当前良好的制造实践制造的新型大型术疫苗菌株的临床评价。

著录项

来源
《The American Naturalist: Devoted to the Conceptual Unification of the Biological Sciences》 |2017年第3期|共8页
作者
Mulligan Mark J.; Stapleton Jack T.; Keitel Wendy A.; Frey Sharon E.; Chen Wilbur H.; Rouphael Nadine; Edupuganti Srilatha; Beck Allison; Winokur Patricia L.; El Sahly Hana M.; Patel Shital M.; Atmar Robert L.; Graham Irene; Anderson Edwin; El-Kamary Samer S.; Pasetti Marcela F.; Sztein Marcelo B.; Hill Heather; Goll Johannes B.;
展开▼
作者单位

Emory Univ Hope Clin Emory Vaccine Ctr Dept Med Div Infect Dis Sch Med 500 Irvin Court Suite 200 Decatur GA 30030 USA;

Univ Iowa SW54-4 GH 200 Hawkins Dr Iowa City IA 52242 USA;

Baylor Coll Med Dept Mol Virol &

Microbiol BCM MS 280 One Baylor Plaza Houston TX 77030 USA;

St Louis Univ Div Infect Dis Allergy &

Immunol Sch Med 1100 South Grand Blvd DRC-8 St Louis MO 63104 USA;

Univ Maryland Ctr Vaccine Dev Sch Med 685 W Baltimore St Suite 480 Baltimore MD 21201 USA;

Emory Univ Hope Clin Emory Vaccine Ctr Dept Med Div Infect Dis Sch Med 500 Irvin Court Suite 200 Decatur GA 30030 USA;

Emory Univ Hope Clin Emory Vaccine Ctr Dept Med Div Infect Dis Sch Med 500 Irvin Court Suite 200 Decatur GA 30030 USA;

Emory Univ Hope Clin Emory Vaccine Ctr Dept Med Div Infect Dis Sch Med 500 Irvin Court Suite 200 Decatur GA 30030 USA;

Univ Iowa SW54-4 GH 200 Hawkins Dr Iowa City IA 52242 USA;

Baylor Coll Med Dept Mol Virol &

Microbiol BCM MS 280 One Baylor Plaza Houston TX 77030 USA;

Baylor Coll Med Dept Mol Virol &

Microbiol BCM MS 280 One Baylor Plaza Houston TX 77030 USA;

Baylor Coll Med Dept Mol Virol &

Microbiol BCM MS 280 One Baylor Plaza Houston TX 77030 USA;

St Louis Univ Div Infect Dis Allergy &

Immunol Sch Med 1100 South Grand Blvd DRC-8 St Louis MO 63104 USA;

St Louis Univ Div Infect Dis Allergy &

Immunol Sch Med 1100 South Grand Blvd DRC-8 St Louis MO 63104 USA;

Univ Maryland Ctr Vaccine Dev Sch Med 685 W Baltimore St Suite 480 Baltimore MD 21201 USA;

Univ Maryland Ctr Vaccine Dev Sch Med 685 W Baltimore St Suite 480 Baltimore MD 21201 USA;

Univ Maryland Ctr Vaccine Dev Sch Med 685 W Baltimore St Suite 480 Baltimore MD 21201 USA;

Emmes Corp 401 North Washington St Suite 700 Rockville MD 20850 USA;

Emmes Corp 401 North Washington St Suite 700 Rockville MD 20850 USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生物科学;
关键词
Tularemia; LVS; Bacterial; Take; Vaccine; Francisella tularensis;

机译：Tularemia;LVS;细菌;服用;疫苗;弗朗西亚·塔尔斯蒂斯;

相似文献

外文文献
中文文献
专利

1. Tularemia vaccine: Safety, reactogenicity, "Take" skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial [J] . Vaccine . 2017,第36期

机译：Tularemia疫苗：安全性，反应源性，“服用”皮肤反应，并在疫苗接种后用新的繁殖疫苗活疫苗菌株 - A 2阶段随机临床试验
2. Cell-mediated and humoral immune responses induced by scarification vaccination of human volunteers with a new lot of the live vaccine strain of Francisella tularensis. [J] . D M Waag, A Galloway, G Sandstrom, Journal of Clinical Microbiology . 1992,第9期

机译：用新的人志愿者吞噬疫苗接种诱导的细胞介导和体液免疫应答，新的大量的Francisella Tularensis活疫苗菌株。
3. Immunogenicity and safety of a novel MMR vaccine (live, freeze-dried) containing the Edmonston-Zagreb measles strain, the Hoshino mumps strain, and the RA 27/3 rubella strain: Results of a randomized, comparative, active controlled phase III clinical trial [J] . Sood Ashwani, Mitra Monjori, Joshi Himanshu Arvind, Human vaccines & immunotherapeutics. . 2017,第7期

机译：含有edmonston-Zagreb麻疹菌株，霍尼诺腮腺炎菌株的新型MMR疫苗（活性，冷冻干燥）的免疫原性和安全性，以及RA 27/3风疹菌株：随机化，比较，活性受控期III临床试验结果
4. PRRS ELISA ANTIBODY RESPONSE CURVES FOLLOWING VACCINATION WITH A MODIFIED LIVE VIRUS PRRS VACCINE (INGELVAC~(R) PRRS ATP) [C] . D. Jordan, D. Polson Congress of the International Pig Veterinary Society . 2000

机译：PRRS ELISA抗体反应后抗疫苗接种后疫苗接种后（INGELVAC〜（R）PRRS ATP）
5. Generation and characterization of an attenuated mutant in a response-regulator gene of Francisella tularensis live vaccine strain (LVS). [D] . Sammons, Wendy L. 2007

机译：图拉弗朗西斯菌活疫苗株（LVS）的应答调节基因中减毒突变体的产生和表征。
6. Tularemia Vaccine: Safety Reactogenicity Take Skin Reactions and Antibody Responses following Vaccination with a New Lot of the Francisella tularensis Live Vaccine Strain - A Phase 2 Randomized Clinical Trial [O] . Mark J. Mulligan, Jack T Stapleton, Wendy A. Keitel, -1

机译：Tularemia疫苗：接种新一批tularensis活疫苗株后的安全性反应原性接受皮肤反应和抗体反应-2期随机临床试验
7. Cell-mediated and humoral immune responses induced by scarification vaccination of human volunteers with a new lot of the live vaccine strain of Francisella tularensis [O] . D M Waag, A Galloway, G Sandstrom, 1992

机译：通过造成人类志愿者造成的细胞介导和体液免疫应答，具有新的众多Francisella Tularensis的活疫苗菌株
8. Cell-Mediated and Humoral Immune Responses Induced by Scarification Vaccination of Human Volunteers with a New Lot of the Live Vaccine Strain of 'Francisella tularensis'. [R] . Waag, D. M., Galloway, A., Sandstrom, G., 1992

机译：新一代'土拉弗朗西斯菌'活疫苗株人类志愿者瘢痕接种诱导细胞介导和体液免疫应答。

Tularemia vaccine: Safety, reactogenicity, 'Take' skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial

摘要

著录项

相似文献

相关主题

期刊订阅