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Factorial Switching Linear Dynamical Systems Applied to Physiological Condition Monitoring

机译:因子交换线性动力学系统在生理状态监测中的应用

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摘要

Condition monitoring often involves the analysis of systems with hidden factors that switch between different modes of operation in some way. Given a sequence of observations, the task is to infer the filtering distribution of the switch setting at each time step. In this paper, we present factorial switching linear dynamical systems as a general framework for handling such problems. We show how domain knowledge and learning can be successfully combined in this framework, and introduce a new factor (the ȁC;X-factorȁD;) for dealing with unmodeled variation. We demonstrate the flexibility of this type of model by applying it to the problem of monitoring the condition of a premature baby receiving intensive care. The state of health of a baby cannot be observed directly, but different underlying factors are associated with particular patterns of physiological measurements and artifacts. We have explicit knowledge of common factors and use the X-factor to model novel patterns which are clinically significant but have unknown cause. Experimental results are given which show the developed methods to be effective on typical intensive care unit monitoring data.
机译:状态监视通常涉及对具有隐藏因素的系统进行分析,这些隐藏因素以某种方式在不同的操作模式之间切换。给定一系列观察结果,任务是推断每个时间步长的开关设置的过滤分布。在本文中,我们提出阶乘切换线性动力系统作为处理此类问题的通用框架。我们展示了如何在此框架中成功地结合领域知识和学习,并介绍了一个新的因子(ȁC;X-factorȁD;)来处理未建模的变异。我们通过将其应用于监控重症监护早产婴儿状况的问题,证明了该模型的灵活性。无法直接观察婴儿的健康状况,但是不同的潜在因素与生理测量和伪影的特定模式相关。我们对常见因素有明确的了解,并使用X因子对具有临床意义但原因未知的新型模式进行建模。实验结果表明,所开发的方法对典型的重症监护室监测数据有效。

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