Identification of the Forms of Vitamin B6 Present in the Culture Media of Vitamin B6 Control Mutants

摘要

An Escherichia coli mutant resistant to isoniazid (WG497) contained 0.6 μmole of extracellular pyridoxamine and pyridoxamine phosphate in the early stationary phase. A suppressed lysine mutant (AT1024) contained 1.4 μmoles of pyridoxal phosphate under the same conditions. The internal concentration of vitamin B6 was one-half of normal for AT1024 and increased fivefold for WG497.