Bone marrow endothelial progenitor cells activate hepatic stellate cells and aggravate carbon tetrachloride induced liver fibrosis in mice via paracrine factors

摘要

Bone marrow derived endothelial progenitor cells ( ‐ s) are increased in chronic liver disease ( ). Their role in hepatic fibrosis and regeneration remains an area of intense studies. We investigated the migration and secretory functions of ‐ s in fibrotic mice liver.