摘要：@@ 自1950年始，非霍奇金淋巴瘤(NHL)在全球的发病率每年增长4%，据美国学者统计，此病的死亡率位居全国恶性肿瘤的第六位［1］。经过20年的不断探索，CHOP方案在NHL综合治疗中的地位已经确定。本文总结CHOP方案治疗47例非霍奇金淋巴瘤患者的近期疗效。rn1 资料和方法rn1.1 研究对象：本文收集1997年10月～1999年8月两个医院血液科收治的47例初治NHL患者，经病理、细胞学确诊，采用CHOP方案治疗。其中男性29例，女性18例；年龄15～79岁，中位年龄49.5岁。根据1971年Ann Arbor国际会议临床分期法［2］，ⅠA期患者6例，ⅠB期患者2例；ⅡA期患者11例，ⅡB期患者3例；ⅢA期患者10例，ⅢB期患者7例；ⅣA期患者3例，ⅣB期患者5例。根据1982年美国国立癌症研究所制定的《国际工作分类法》［3］，低度恶性患者6例(12.8%)，中度恶性患者26例(55.32%)，高度恶性患者13例(28%)，未定型2例(4.26%)。rn1.2 治疗方法：CHOP方案［4］：环磷酰胺750mg／m2 iv d1，阿霉素50mg／m2 iv d1，长春新碱1.4mg／m2 iv d1(最多2mg)，强的松100mg／m2 iv d1～d5。每3周一个周期，共用药6～8个周期，取得CR后至少加用两个周期。rn1.3 判定标准：根据实体瘤的疗效评定标准［5］，完全缓解(CR)：可见病变完全消失，超过1个月；部分缓解(PR)：肿块缩小50%以上，时间不少于4周；无变化(NC)：肿块缩小不到50%或增大未超过25%；病情进展(PD)：一个或多个病变增大25%以上或出现新病变。毒副反应：参照抗癌药物急性与亚急性毒性反应分度标准［5］。rn1.4 统计方法：采用x2检验进行统计学处理。
摘要：Objective：To probe into the clinical application of hepatosplenic interventional therapy for treatment of liver cancer with portal hypertension and hypersplenism.Methods:86 patients received hepatic arterial chemoinfusion(HAI)and/or chemoembolization(HAE)with partial spleen embolization(PSE).The PSE was carried out once in 60 patients and twice or more in 26 patients.Results:The postoperative white blood cell and thrombocyte count were more than preoperation.The average regeneration rate were 219.2% and 297.9%,after operation 2 months respectively.The syndrome of portal hypertension were decreased.The survival rates for 123 year were 58.1%,30.2%,15.1% respectively.Conclusions:The hepatosplenic interventional therapy is a safe and an effective one to treat liver cancer with portal hypertension and hypersplenism.%目的 探讨肝脾双介入治疗肝癌伴门脉高压及脾亢的作用。方法 86例患者在肝癌介入治疗的同时行部分脾栓塞术(PSE)116次，其中26例行2次以上PSE。结果 全部病例术后白细胞及血小板均恢复正常，术后2个月与术前比较平均增高率分别为219.2%、297.9%，门脉高压症状减轻，1、2、3年存活率分别为58.1%、30.2%、15.1%。结论 肝脾双介入治疗肝癌伴门脉高压、脾亢是一种安全有效的方法。
摘要：Objective：To investigate the clinical effects of the maxillary denture with pure titanium casting denture base．Methods：Maxillary complete dentures with titanium and cobalt-chromium alloy casting bases were applied to 60 patients．Compare the clinic effects between them over a period of 3 months．Followed up one year，investigate the color of the pure titanium casting bases and the condition of oral mucosa．Results：The stability and comfort of maxillary dentures with pure titanium casting bases were more improved than that of the Co-Cr casting bases．Conclusions：Pure titanium casting base is feasible for maxillary complete denture．%目的 观察纯钛铸造基托修复上颌全口义齿的临床疗效。方法 随访1997～1999年戴用纯钛及钴铬合金铸造基托的上颌全口义齿患者60例，以美观度、语音功能、咀嚼功能、固位功能、舒适性五个方面作为评价指标。结果 纯钛铸造基托修复上颌全口义齿在固位功能及舒适性方面比钴铬合金铸造基托有明显提高(P＜0.05)。结论 纯钛铸造基托上颌全口义齿具有优良的修复效果。
摘要：Objective：To study the levels of serum Vitamin A and Vitamin E in infantile pneumonia．Methods：In 50 cases with infantile pneumonia and 50 cases controls，Serum Vitamin A and Vitamin E level were simultaneously determined by RP-HLPC method．Results：The serum Vitamin A levels of the cases with infantile pneumonia and healthy infants were 0.935±0.433μmol／L and 1.211±0.356 μmol／L，respectively（t＝3.582，P＜0.001）．The incidences of preclinical Vitamin A deficiency，dubious diagnosis were 32％，38％ and 4％，28％ respectively （x2＝19.014，P＜0.001)and the levels of serum Vitamin E was not markedly changed as compared with the normal controls．Conclusions：It was suggested that the serum Vitamin A level of infants with pneumonia was clearly lower than that of the healthy infants and the incidence of preclinical Vitamin A deficiency was significantly higher than that of the healthy control group．%目的 测定婴幼儿肺炎血清维生素A和维生素E含量，探讨其状况与疾病相互关系，为临床防治提供参考。方法 采用反相高效液相色谱法，同时测定血清中维生素A、维生素E含量，对50例婴幼儿肺炎住院患儿进行检测并与同期50名体检健康婴幼儿对照。结果 婴幼儿肺炎组维生素A均值明显低于健康组(t＝3.582，P＜0.001)；亚临床维生素A缺乏及可疑诊断的检出率明显高于健康对照组(X2＝19.014，P＜0.001）。婴幼儿肺炎组维生素E水平与对照组比较，差异不显著(P＞0.05)。结论 婴幼儿肺炎血清中维生素A状况低于健康者，而亚临床缺乏的发生率高于健康婴幼儿。
