Manganese Levels in Plant-based Diets May Exceed U.S. Dietary Recommendations-an Examination of the Ornish and DASH Diets (P24-011-19)

摘要

ObjectivesManganese (Mn) is a dietary mineral critical for life, yet high levels of Mn can lead to symptoms of toxicity. The Mn content in food varies considerably and is most concentrated in plant-based foods, whole grains, legumes, nuts, etc. The adult adequate intake (AI) for Mn is 1.8 mg/day for women and 2.3 mg/day for men while the tolerable upper intake level (UL) is 11 mg/day for men and women. Mn absorption and bioavailability of Mn is affected by an individual's nutrition status and dietary factors. When Fe status is low Fe absorption is enhanced, subsequently increasing Mn absorption as well. Increasing evidence in support of the heart health benefits of plant-based diets has led to a rise in medically prescribed modern diets such as the Ornish diet. By design, this and other plant-based diets have a higher propensity to include Mn-rich foods. It is hypothesized that the average Mn content of the plant-based, Ornish diet will be significantly higher than that of the omnivorous Dietary Approaches to Stop Hypertension (DASH) diet. The objective of this research study is to assess the Mn levels in medically prescribed diets and compare them to current dietary standards.