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Prevalence of hepatitis C virus infection and its related risk factors in drug abuser prisoners in Hamedan - Iran

机译:伊朗哈马丹吸毒者囚犯中丙型肝炎病毒感染的流行及其相关危险因素

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摘要

AIM: Recent studies in Iran has shown that prevalence of hepatitis C virus (HCV) infection among Iranian prisoners is high, in spite of low HCV seroprevalence in general population.METHODS: This study was carried out in the central prison of Hamedan - Iran, in year 2002. Inmates were interviewed using a standard questionnaire including demographic, imprisonment history and HCV-related risk behaviors items. Thereafter, the sera drawn from the participants were tested for anti-HIV and anti-HCV antibodies.RESULTS: A total number of 427 drug abuser inmates participated in our study. Three hundred and ninety-seven (93%) were men and 30 (7%) were women. Total number of IV drug abusers (IDA) and non-IV drug abusers (NIDA) was 149 (34.9%) and 278 (65.1%), respectively. The overall rate of antibody positivity among inmates was 0.9% for HIV and 30% for HCV. Of all IDAs, 31.5% and of NIDAs, 29.1% had serological evidence of HCV infection.CONCLUSION: The seroprevalence of HCV infection among drug abuser prisoners in comparison with the general population in Iran, is very high (30% vs in italics 0.2%). Our results indicate the importance of policies to prevent transmission of HCV infection during and following incarceration.
机译:目的:伊朗的最新研究表明,尽管普通人群中的丙型肝炎病毒感染率较低,但伊朗囚犯中的丙型肝炎病毒(HCV)感染率仍然很高。方法:这项研究是在伊朗哈马丹市中心监狱进行的,在2002年。使用标准调查表对囚犯进行了采访,包括人口统计,监禁历史以及与HCV相关的危险行为项目。此后,从参与者抽取的血清进行了抗HIV和抗HCV抗体检测。结果:共有427名吸毒者囚犯参加了我们的研究。男性为三百九十七(93%),女性为三十(7%)。静脉吸毒者(IDA)和非静脉吸毒者(NIDA)的总数分别为149(34.9%)和278(65.1%)。囚犯中抗体阳性的总体比率为:HIV为0.9%,HCV为30%。在所有IDA中,有31.5%的NIDA和29.1%的人有HCV感染的血清学证据。结论:与伊朗普通人群相比,吸毒者囚犯的HCV感染的血清阳性率很高(30%,斜体字为0.2%) )。我们的结果表明,在监禁期间和之后预防HCV感染传播的政策很重要。

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