method of identifying a subject at risk of developing cryoglobulinemia vasculitis and hepatitis c virus-associated (hvc) B-cell malignancy, method of identifying a subject at risk of developing cryoglobulinemia vasculitis or b-cell malignancy associated with hepatitis c virus (hvc) infection, method of treating cryoglobulinemic vasculitis and hcv-associated B-cell malignancy in one subject, method of identifying a subject at risk of developing hepatitis c virus-associated malignancy (hcv) and kit

摘要

The invention provides methods and compositions for early diagnosis and treatment of a disease associated with a specific antibody by employing the detection of a cross-idiotypic epitope on the specific antibody to detect the cells that produce the antibody before the development of clinical symptoms of the disease.