DIFFERENT MEANS OF SOLUBILIZATION OF MEMBRANE PROTEINS FOR NATIVE MS

摘要

Membrane proteins are of high interest, but still underrepresented in research due to the inherent difficulties for many investigation methods, arising from their hydrophobic nature. Depending on the feature of the membrane protein complex the researcher is interested in (protein stoichiometry, lipid affinity, annular lipids...), different means of solubilisation can enable MS analysis.