The present invention includes a syringe including a fine needle that invades the lesion tissue of a subject, a cylinder connected to the fine needle, and a plunger that reciprocates along the cylinder; a plunger driver for reciprocating the plunger so that a negative pressure or a positive pressure is formed in the fine needle; a cylinder driving unit that shakes or reciprocates the cylinder so that the fine needle is shaken or reciprocated; and a control unit controlling the plunger driving unit so that a negative pressure is formed in the fine needle to suck the lesion tissue, and controlling the cylinder driving unit so that the fine needle swings or reciprocates along a preset path. It is about.
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