PROCEDURE FOR OBTAINING 3- (2- (4- (6-FLUORO-BENZO (D) ISOXAZOL-3-IL) PIPERIDIN-1-IL) -ETIL) -2-METHYL-6,7,8,9- TETRAHIDRO-4H-PIRIDO- (1,2-A) PIRIMIDIN-4-ONA.

摘要

PROCEDURE FOR OBTAINING 3-2- [4- (6-FLUORO-BENZO [D] ISOXAZOL-3-IL) -PIPERIDIN-1-IL] -ETILL-2-METHYL-6,7,8,9-TETRAHYDRO -4H-PIRIDO [1,2, -A] -PIRIMIDIN-4-ONA. THE PROCEDURE CONSISTS OF REACTIONING 3- (2-AMINOETHYL) -2-METHYL-6,7,8,9-TETRAHYDRO-4H-PIRIDO [1,2-A] PIRIMIDIN-4-ONA, OF FORMULA II, WITH COMPOUNDS OF GENERAL FORMULA III, WHERE "Y" AND "Z" ARE OUTGOING, EQUAL OR DIFFERENT GROUPS, SUCH AS HALOGEN OR A RENT OR ARILSULFONILOXI GROUP, IN THE PRESENCE OF A SUITABLE SOLVENT AND BASE, TO PROVIDE 3-2 - [4-6-FLUORO-BENZO [D] ISOXAZOL-3-IL) -PIPERIDIN-1-IL] ETIL-2-METHYL-6,7,8,9-TETRAHIDRO-4H-PIRIDO [L, 2-A ] PIRIMIDIN-4-ONA OF GENERAL FORMULA I. SUCH COMPOUND HAS PHARMACEUTICAL APPLICATIONS FOR ITS ANTIPSYCHOTIC PROPERTIES. THE PRODUCTS OF FORMULAS II AND III, NECESSARY FOR THE DEVELOPMENT OF THE PRESENT INVENTION, ARE ALSO CLAIMED.