NEW MATERIAL:A compound expressed by formula l [R1 is OH or lower alkoxy; R2 is (protected) carboxyl; R3 is lower (halogenated) alkyl or lower alkenyl]. EXAMPLE:7-[(Z)-2-(2-Aminothiazol-4-yl)-2-hydroxyiminoacetamido[-3-[(Z) -3-(N methylcarbamoyloxy]-1-propenyl]-3-cephem-4-carboxylic acid sodium salt expressed by formula II. USE:An antimicrobial agent. PREPARATION:A compound expressed by formula III [R4 is (protected) amino; R5 is (protected) OH or lower alkoxy] is reacted with an isocyanate expressed by the formula R3-N=C=O and as necessary, protecting group of the reaction product is eliminated.
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机译：新材料：由式l [R 1]表示的化合物是OH或低级烷氧基; R 2是（保护的）羧基; R 3为低级（卤代）烷基或低级烯基]。实施例：7-[（Z）-2-（2-氨基噻唑-4-基）-2-羟基亚氨基乙酰胺基[-3-[（Z）-3-（N甲基氨基甲酰氧基] -1-丙烯基] -3-cephem-4式II表示的-羧酸钠盐用途：抗菌剂制备：式III表示的化合物[R 4是（保护的）氨基; R 5是（保护的）OH或低级烷氧基）反应用式R 3 -N ＝ C ＝ O表示的异氰酸酯，根据需要除去反应产物的保护基。
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