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Prostaglandin-containing fat emulsion and method for producing the same

机译:含前列腺素的脂肪乳剂及其制备方法

摘要

Provided are a prostaglandin-containing fat emulsion excellent in stability of an emulsion as well as stability of prostaglandin and a method for producing the same. The prostaglandin-containing fat emulsion comprises at least prostaglandin, a fat, an emulsifier containing phosphatidylethanolamine in an amount of 2% by weight or less and water as constituents and is characterized in that a content of the fat is from 0.05 to 20 mg/mL, a weight ratio of prostaglandin to the fat (prostaglandin/fat) is from 0.0005 to 20 (with the proviso that a total content of prostaglandin and the fat is up to 25 mg/mL), a weight ratio of the emulsifier to the fat (emulsifier/fat) is from 1 to 600, and a fatty acid having 6 to 22 carbon atoms or a salt thereof is not contained.
机译:本发明提供一种乳液稳定性和前列腺素的稳定性优异的含前列腺素的脂肪乳剂及其制造方法。含前列腺素的脂肪乳剂至少包含前列腺素,脂肪,以2重量%以下的比例含有磷脂酰乙醇胺和水作为成分的乳化剂,其特征在于,脂肪的含量为0.05〜20mg / mL。 ,前列腺素与脂肪的重量比(前列腺素/脂肪)为0.0005至20(前提是前列腺素与脂肪的总含量不超过25 mg / mL),乳化剂与脂肪的重量比(乳化剂/脂肪)为1至600,并且不包含具有6至22个碳原子的脂肪酸或其盐。

著录项

  • 公开/公告号JP5582635B2

    专利类型

  • 公开/公告日2014-09-03

    原文格式PDF

  • 申请/专利权人 テクノガード株式会社;

    申请/专利号JP20090550552

  • 发明设计人 鍋田 喜一郎;

    申请日2009-01-22

  • 分类号A61K31/5575;A61K47/24;A61K9/107;A61K47/10;A61K47/32;A61K47/38;A61K47/36;A61P9/10;A61K47/12;A61P27/02;A61P43;A61K47/44;

  • 国家 JP

  • 入库时间 2022-08-21 16:13:15

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