Bioelectrical impedance vector analysis, phase-angle assessment and relationship with malnutrition risk in a cohort of frail older hospital patients in the United Kingdom

摘要

AbstractObjective Bioelectrical impedance vector analysis (BIVA) and phase angle (PA) have been shown previously to indicate relative nutritional status in patients. The aim of this study was to investigate the application of {BIVA} and {PA} assessments in a cohort of frail older hospital patients and compare these assessments with malnutrition risk screening by {MUST} (Malnutrition Universal Screening Tool), and the MNA-SF® (Mini-Nutritional Assessment-Short Form). Methods Sixty-nine patients (n = 44 men; n = 25 women; age 82.1 ± 7.6 y range 62â-96 y; body mass index 25.8 ± 5.4 kg/m2 range 16.6â-45.1 kg/m2) were recruited from hospital wards specializing in the care of frail older individuals from the United Kingdom. Bioelectrical impedance assessment was performed at 50 khz frequency, {BIVA} was performed using raw impedance data, {PA} was calculated, and data were compared against reference population groups. Patients were categorized by malnutrition risk by {MUST} and MNA-SF. Results {BIVA} indicated that the men and women in the study were significantly different from reference population groups (P  0.0001), with a noticeable reduced capacitive reactance (xC) component. The group mean {PA} was 4.6° ± 1.1° (2.4°â-9.2°). The mean {PA} for men was 4.7° ± 1.3° (2.4°â-9.2°), and for women it was 4.5° ± 0.7° (2.8â-6.0°). Group {PA} correlated with MNA-SF score (P = 0.05). {MUST} categorized patients predominantly at low risk for malnutrition (80%); whereas MNA-SF was at risk (46%) and malnourished (45%). Conclusions The significant reduction in xC component and {PA} is consistent with other studies and is indicative of a reduced body cell mass and nutritional status with aging and illness. The general trend in MNA-SF scoring was more consistent with these patterns as a group; but requires clarification in larger cohorts. Future studies are necessary with an aim to improve and optimize care of frail older people.