Hepatitis B Immune Globulin Used to Inactivate Hepatitis B Virus in Injectable Biological Products

摘要

The utilization of hepatitis B immune globulin as a preparation for preventing transmission of the hepatitis B virus (HBV) by injectable biologics, by incubation of the injectable biologics and hepatitis B immune globulin together in vitro prior to administration to patient. The hepatitis B immune globulin is utilized in a dosage of 5 ml and in a preferred titer of 1 to 100,000. The titer may vary to a range of 1 to 100 concentration with an intermediate range of 1 to 1,000; ranging down to 1 to 100,000. Also there may be used other immune globulins such as immune serum globulin (ISG).