The Mutagenic Potential of 2,4-diamino-6-(2'-napthyl-sulfonyl) quinazoline

摘要

The mutagenic potential of 2,4-diamino-6-(2'napthyl-sulfonyl) quinazoline (WR158122) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .001 mg/plate to 3.2 x 10 to the minus 7th power mg/plate. It was determined that the test substance did not have mutagenic potential.