An Efficient and Highly Selective Method for the Synthesis of 3-Arylbenzo-quinoline Derivatives Catalyzed by Iodine via Three-Component Reactions

摘要

A mild, efficient and highly selective method for the synthesis of benzo[/]qumoline derivatives via three-component reactions of arylaldehydes, naphthalen-2-amine and ketones or P-keto esters using iodine as catalyst is described. It should be noted that only one product was obtained, with high selectivity, when ketones or |3-keto esters with two different a-hydrogen atoms were chosen as reactants.