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A Simple and Efficient Synthesis of Highly Substituted Indeno12-bpyrrole and Acenaphtho12-bpyrrole Derivatives by Tandem Three-Component Reactions

机译:串联三组分反应简单高效合成高取代度茚并12-b吡咯和Ac 12-b吡咯衍生物

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摘要

A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.
机译:通过色胺/苄胺,1,3-二羰基多米诺三组分反应高效合成高度取代的茚并[1,2-b]吡咯和[1,2-b]吡咯衍生物的绿色,便捷和串联程序描述了化合物和茚三酮/烯醌。该方法的显着特征是反应条件温和,收率高,操作简便且对环境无害。

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