The Inhibitory Effect of Prunioside A Acyl Derivatives on NO Production in RAW 264.7 Cell

摘要

Prunioside A is a unique,highly oxidized monoterpene glycoside isolated from the methanol extract of Spiraea prunifolia var.Simpliciflora's root.The ester derivatives were synthesized from the hydrolyzed compounds of prunioside A by beta-glucosidase.The derivatives showed suppressive effects on the generation of nitric oxide in murine machrophage-like RAW 264.7 cells stimulated by lipopolysaccharide and interferon-gamma.