R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability

Chen Hsuan-Yu; Yu Sung-Liang; Ho Bing-Ching; Su Kang-Yi; Hsu Yi-Chiung; Chang Chi-Sheng; Li Yu-Cheng; Yang Shi-Yi; Hsu Pin-Yen; Ho Hao; Chang Ya-Hsuan; Chen Chih-Yi; Yang Hwai-I; Hsu Chung-Ping; Yang Tsung-Ying; Chen Kun-Chieh; Hsu Kuo-Hsuan; Tseng Jeng-Sen; Hsia Jiun-Yi; Chuang Cheng-Yen; Yuan Shinsheng; Lee Mei-Hsuan; Liu Chia-Hsin; Wu Guan-I; Hsiung Chao A.; Chen Yuh-Min; Wang Chih-Liang; Huang Ming-Shyan; Yu Chong-Jen; Chen Kuan-Yu; Tsai Ying-Huang; Su Wu-Chou; Chen Huei-Wen; Chen Jeremy J. W.; Chen Chien-Jen; Chang Gee-Chen; Yang Pan-Chyr; Li Ker-Chau

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R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability

机译：R331W致癌基因YAP1的错义突变是肺腺癌的生殖危险等位基因，具有医疗作用

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《Journal of Clinical Oncology》 |2015年第20期|共16页
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Chen Hsuan-Yu; Yu Sung-Liang; Ho Bing-Ching; Su Kang-Yi; Hsu Yi-Chiung; Chang Chi-Sheng; Li Yu-Cheng; Yang Shi-Yi; Hsu Pin-Yen; Ho Hao; Chang Ya-Hsuan; Chen Chih-Yi; Yang Hwai-I; Hsu Chung-Ping; Yang Tsung-Ying; Chen Kun-Chieh; Hsu Kuo-Hsuan; Tseng Jeng-Sen; Hsia Jiun-Yi; Chuang Cheng-Yen; Yuan Shinsheng; Lee Mei-Hsuan; Liu Chia-Hsin; Wu Guan-I; Hsiung Chao A.; Chen Yuh-Min; Wang Chih-Liang; Huang Ming-Shyan; Yu Chong-Jen; Chen Kuan-Yu; Tsai Ying-Huang; Su Wu-Chou; Chen Huei-Wen; Chen Jeremy J. W.; Chen Chien-Jen; Chang Gee-Chen; Yang Pan-Chyr; Li Ker-Chau;
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1. R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability [J] . Chen Hsuan-Yu, Yu Sung-Liang, Ho Bing-Ching, Journal of Clinical Oncology . 2015,第20期

机译：R331W致癌基因YAP1的错义突变是肺腺癌的生殖危险等位基因，具有医疗作用
2. Germline mutations in driver oncogenes and inherited lung cancer risk independent of smoking history [J] . OxnardG.R., NguyenK.-S.H., CostaD.B. Journal of the National Cancer Institute . 2014,第1期

机译：驾驶员致癌基因中的种系突变和遗传性肺癌风险与吸烟史无关
3. Early onset hereditary papillary renal carcinoma: germline missense mutations in the tyrosine kinase domain of the met proto-oncogene. [J] . Schmidt LS, Nickerson ML, Angeloni D, The Journal of Urology . 2004,第4aPta1期

机译：早发性遗传性乳头状肾癌：met原癌基因酪氨酸激酶结构域的种系错义突变。
4. Influence of XPD variant alleles on p53 mutations in lung tumors of nonsmokers and smokers [C] . Sai-Mei Hou, Annamaria Kannio, Sabrina Angelini, International Symposium of Radiation and Homeostasis . 2002

机译：XPD变异等位基因对非摩托车肺肿瘤P53突变的影响
5. Examining functional variation in oncogene biology: The role of somatic mutations and germline variation on c-Myc and c-Myb [D] . Turner, Scott Andrew 2014

机译：检查癌基因生物学中的功能变异：体细胞突变和种系变异对c-Myc和c-Myb的作用
6. Two Germline Missense Mutations at Codons 804 and 806 of the RET Proto‐oncogene in the Same Allele in a Patient with Multiple Endocrine Neoplasia Type 2B without Codon 918 Mutation [O] . Akira Miyauchi, Hitoyasu Futami, Noritaka Hai, 1999

机译：患有多内分泌肿瘤2B型而无密码子918突变的患者同一等位基因中RET原癌基因密码子804和806的两个生殖系错义突变
7. Two Germline Missense Mutations at Codons 804 and 806 of theRETProto-oncogene in the Same Allele in a Patient with Multiple Endocrine Neoplasia Type 2B without Codon 918 Mutation [O] . Akira Miyauchi, Hitoyasu Futami, Noritaka Hai, 1999

机译：在具有多个内分泌瘤型2b的患者的同一等位基因中，在具有多个内分泌瘤形成2b的同一等位基因中，在具有密码子918突变的患者的同一等位基因中的两个种系畸形突变
8. Exploiting RhoA Mutations in Diffuse Gastric Adenocarcinoma and Targeting Intertwined RhoA and Yap1 Pathways for Therapeutic Advantage. [R] . Ajani, J. 2017

机译：利用弥漫性胃腺癌中的Rhoa突变和靶向交织的Rhoa和Yap1途径获得治疗优势。

R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability

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