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Exploiting RhoA Mutations in Diffuse Gastric Adenocarcinoma and Targeting Intertwined RhoA and Yap1 Pathways for Therapeutic Advantage.

机译：利用弥漫性胃腺癌中的Rhoa突变和靶向交织的Rhoa和Yap1途径获得治疗优势。

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作者
Ajani, J.;
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年度 2017
页码 1-34
总页数 34
原文格式 PDF
正文语种 eng
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关键词
Diffuse Gastric Adenocarcinoma;

机译：弥漫性胃腺癌;

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专利

1. Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer [J] . Zhang Haisheng, Schaefer Antje, Wang Yichen, Cancer discovery. . 2020,第2期

机译：功能性RhoA突变促进局灶性粘附激酶活化和衍生弥漫性胃癌
2. Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers [J] . Cho Soo Young, Park Jun Won, Liu Yang, Gastroenterology . 2017,第2期

机译：零星早熟弥漫性胃癌具有高频率的体细胞CDH1改变，但与晚期发作癌症相比，体细胞突变突变的低频率
3. RhoA Mutations Identified in Diffuse Gastric Cancer [J] . ZhouJ., HayakawaY., WangT., Cancer Cell . 2014,第1期

机译：在弥漫性胃癌中发现RhoA突变
4. Cationic amphiphilic polymeric micelle as therapeutic siRhoA carrier for Axonal Regeneration in spinal cord injury [C] . So-Jung Gwak, Christian Macks, Da Un Jeong, Society for Biomaterials annual meeting and exposition . 2017

机译：阳离子两亲性聚合物胶束作为治疗脊髓损伤中轴突再生的siRhoA载体
5. The role of RhoA interacting proteins in the Nogo signalling pathway of axon outgrowth inhibition. [D] . Alabed, Yazan Z. 2009

机译：RhoA相互作用蛋白在轴突生长抑制的Nogo信号通路中的作用。
6. Inactivating Mutations in GNA13 and RHOA in Burkitt’s Lymphoma and Diffuse Large B cell Lymphoma: A Tumor Suppressor Function for the Gα13/RhoA Axis in B Cells [O] . Morgan O’Hayre, Asuka Inoue, Irina Kufareva, -1

机译：Burkitt淋巴瘤和弥漫性大B细胞淋巴瘤中GNA13和RHOA的失活突变：B细胞中Gα13/ RhoA轴的肿瘤抑制功能
7. Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers [O] . Soo Young Cho, Jun Won Park, Yang Liu, 2017

机译：零星早熟弥漫性胃癌具有高频率的体细胞CDH1改变，但与晚期发作癌症相比，体细胞突变的低频频率

Exploiting RhoA Mutations in Diffuse Gastric Adenocarcinoma and Targeting Intertwined RhoA and Yap1 Pathways for Therapeutic Advantage.

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