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Antibacterial study and fatty acid analysis of lipids of the sponge Myrmekioderma granulata

机译:海绵Myrmekioderma granulata脂质的抗菌研究和脂肪酸分析

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摘要

The composition of the lipophilic extract of the sponge Myrmekioderma granulata (Esper) collected from 13 m depth of the Bay of Bengal of the Orissa coast was investigated. Fatty acids as well as volatiles and sterols were identified. 4,8,12-Trimethyltridecanoic acid was identified for the first time along with the important PUFAs such as linoleic acid (n-6, C18:2), dihomo-gamma-linolenic acid (n-6, C20:3), 5,8,11,14-eicosatetraenoic acid (n-3, C20:4), and 5,8,11,14,17-eicosapentaenoic acid (EPA) (n-3, C20:5) from this species. The branched polyunsaturated fatty acids like br-C26:2, 25-methyl-5,9-heptacosadienoic acid and 24-methyl-5,9heptacosadienoic acid were also identified by GC-MS. The lipid extract exhibited limited activity against different pathogens.
机译:研究了从奥里萨邦(Orissa)海岸孟加拉湾(Bengal Bay)的13 m深度收集的海绵Myrmekioderma granulata(Esper)的亲脂性提取物的组成。鉴定出脂肪酸以及挥发物和固醇。首次鉴定出4,8,12-三甲基十三烷酸以及重要的PUFA,例如亚油酸(n-6,C18:2),二高-γ-亚麻酸(n-6,C20:3),5该物种的8,11,14-二十碳四烯酸(n-3,C20:4)和5,8,11,14,17-二十碳五烯酸(EPA)(n-3,C20:5)。还通过GC-MS鉴定了支链多不饱和脂肪酸,如br-C26:2、25-甲基-5,9-庚二碳二烯酸和24-甲基-5,9庚二碳二烯酸。脂质提取物对不同病原体的活性有限。

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