Method for concentration based analysis of lipid fatty acids and its use in determining the likelihood that a patient is at risk for diabetes

摘要

A new method for determining and reporting lipid fatty acids compositions and its use in diagnosing diabetes is disclosed. Adding internal standards, which are true analogs of the fatty acids to be analyzed, to blood serum or plasma samples before performing a gas chromatographic analysis of the fatty acids allows the results of the analysis to be reported in absolute terms as, for example, mg/L, instead of in relative percentages. Reporting the results as absolute concentrations reveals statistically significant differences in levels of various lipid fatty acids between persons having and not having diabetes.