首页> 外国专利> a preparation which reduces a concentration of a free fatty acid and / or fibrinogen in the blood, an agent for reducing the amount of a free fatty acid in the blood, an agent for reducing the amount of fibrinogen in the blood, a method for preventing or treating hyperacidemia of free fatty acid, metabolic syndrome, type II diabetes, complications caused by type II diabetes, lipotoxicity, abnormal lipid metabolism, glucose intolerance, impaired insulin secretion, liver fat, hypo-high density lipoproteinemia, or thrombosis, and use of a preparation

a preparation which reduces a concentration of a free fatty acid and / or fibrinogen in the blood, an agent for reducing the amount of a free fatty acid in the blood, an agent for reducing the amount of fibrinogen in the blood, a method for preventing or treating hyperacidemia of free fatty acid, metabolic syndrome, type II diabetes, complications caused by type II diabetes, lipotoxicity, abnormal lipid metabolism, glucose intolerance, impaired insulin secretion, liver fat, hypo-high density lipoproteinemia, or thrombosis, and use of a preparation

机译:降低血液中游离脂肪酸和/或纤维蛋白原浓度的制剂,降低血液中游离脂肪酸含量的试剂,降低血液中纤维蛋白原含量的试剂,预防方法或治疗游离脂肪酸高酸血症,代谢综合征,II型糖尿病,II型糖尿病引起的并发症,脂毒性,脂质代谢异常,葡萄糖耐受不良,胰岛素分泌受损,肝脂肪,低密度脂蛋白血症或血栓形成,以及使用准备

摘要

PREPARATION THAT REDUCES A CONCENTRATION OF A FREE FATTY ACID AND / OR FIBRONOGEN IN THE BLOOD, AGENT FOR REDUCING THE QUANTITY OF A FREE FATTY ACID IN THE BLOOD, AGENT FOR REDUCING THE AMOUNT OF FIBRINOGEN IN THE BLOOD, METHOD OF DETERMINATION OF TREATMENT OF TREATMENT FREE FATTY ACID, METABOLIC SYNDROME, DIABETES TYPE II, COMPLICATIONS CAUSED BY DIABETES TYPE II, LIPOTOXICITY, ABNORMAL PILID METABOLISM, INTOLERANCY TO GLUCOSE, HARMFUL HYDROPULUS, HYDRANT, HYDROPULUS, A PREPARATION It is the preparation of a preparation (pharmaceutical composition) to reduce a concentration of a free fatty acid and / or fibrinogen in the blood. The preparation contains a statin agent comprising at least one statin compound having a benzopyridine skeletal structure (for example, pitavastatin) and a fibrate agent (for example, fenofibrate). The preparation is useful as a preventive or treatment agent for free fatty acid hyperacidemia, metabolic syndrome, or type II diabetes.
机译:减少血液中游离脂肪酸和/或纤维蛋白原浓度的制剂,用于降低血液中游离脂肪酸数量的试剂,用于降低血液中纤维蛋白原含量的试剂,用于确定治疗方法的方法游离脂肪酸,代谢综合征,II型糖尿病,II型糖尿病引起的并发症,脂肪分解,异常的脂质代谢,对葡萄糖的无耐受性,有害的羟基磷灰石,水合物,羟基磷灰石,药物制剂是一种预备制剂(制备方法)血液中游离脂肪酸和/或纤维蛋白原的浓度。该制剂包含他汀类药物,其包括至少一种具有苯并吡啶骨架结构的他汀类化合物(例如匹伐他汀)和贝特类药物(例如非诺贝特)。该制剂可用作游离脂肪酸高酸血症,代谢综合征或II型糖尿病的预防剂或治疗剂。

著录项

  • 公开/公告号BRPI0621942A2

    专利类型

  • 公开/公告日2011-10-18

    原文格式PDF

  • 申请/专利权人 ASKA PHARMACEUTICAL CO. LTD.;

    申请/专利号BR2006PI21942

  • 申请日2006-08-04

  • 分类号A61K31/47;A61K31/216;A61P1/16;A61P1/18;A61P3;A61P3/06;A61P3/08;A61P3/10;A61P7/02;

  • 国家 BR

  • 入库时间 2022-08-21 18:07:10

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