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Radiosurgery for Miscellaneous Skull Base Tumors

机译:杂项颅底肿瘤的放射外科

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Stereotactic radiosurgery has become an integral part of conventional and advanced skull base surgery. Despite the advances in skull base techniques, the goal of total resection of such tumors is often problematic and associated with significant risk to critical structures of the skull base, including those within the cavernous sinus, those in the petrous apex, and the jugular bulb. Aggressive resection of such tumors sometimes results in severe adverse neurological events, ranging from permanent extraocular movement deficits to hearing loss, facial weakness, and difficulties with vagal and glossopharyngeal function. Gamma Knife radiosurgery is a primary alternative option for these patients. It minimizes the risks of open surgical techniques and preserves existing cranial nerve function in most patients and achieves tumor growth arrest. Adjuvant radiosurgery is used for larger tumors after their initial partial resection. Gamma Knife radiosurgery becomes an adjuvant tool to provide long-term tumor growth control of a significantly reduced tumor volume.
机译:立体定向放射外科手术已成为常规和高级颅底手术的组成部分。尽管颅骨基底技术取得了进步,但这种肿瘤全切除的目标常常是有问题的,并且与颅骨基底的关键结构(包括海绵窦内的,尖顶的和颈静脉的那些)的重大风险有关。积极切除此类肿瘤有时会导致严重的不良神经系统事件,从永久性眼外运动缺陷到听力丧失,面部无力以及迷走神经和舌咽功能困难。伽玛刀放射外科手术是这些患者的主要替代选择。它最大程度地降低了开放手术技术的风险,并保留了大多数患者现有的颅神经功能,并实现了肿瘤生长的抑制。初次部分切除后,较大的肿瘤应使用辅助放射外科手术。伽玛刀放射外科手术成为一种辅助工具,可提供对肿瘤体积明显减少的长期肿瘤生长控制。

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