Modulation of Gene Expression by Antimutagens in Human Cells Differing in the Sensitivity to Mutagens

摘要

Evaluation of gene expression allows determination of the level of synthesized product. The parameters of expression of the majority of genes for certain reasons vary, and the study of gene expression makes it possible to identify the indices of sensitivity of human cells to various exogenous factors (radiation, chemical mutagens, etc.), to detect specific molecular subtypes and their expression levels to assess the risk of development of tumors and some human pathologies, as well as to predict the cell response to therapeutic intervention.