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Effect of Pressurized Soy Protein Isolate upon the Growth and Antioxidants Functions of SD Rat

机译:加压大豆分离蛋白对SD大鼠生长和抗氧化功能的影响

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The objective of this study is to specify the effect of pressurized soy protein isolate (pSPI), upon the physical development, growth hormones and antioxidants functions of SD rats. The methodology depends on the selection of one hundred male SD rats, divided randomly into 5 groups. Each group consists of 20 rats. The groups will be defined as one blank control group, three groups with pSPI at low, medium and high doses and another control group with native soy protein isolates (nSPI). Low, medium and high doses are represented by 0.333 g/kg, 1.667 g/kg and 3.333 g/kg pSPI per weight, respectively. The native soy protein isolate is represented by 3.333 g/kg nSPI per weight. In every group, four animals will be taken out to collect the blood samples and analyze insulin like growth factor-I, growth hormone, thyroid stimulating hormone, thyroxine and triiodothyronin. The other SD rats will be subjected to feeding for 63 consecutive days. The body weight, the body length and food intake of each rat are measured. The total antioxidant capacity, superoxide dismutase (SOD), malondialdehyde and Glutathione Peroxidase in liver and serum of each rat will be analyzed. The results indicated that the groups with medium and high dose of pSPI result in an obvious increase in the body weight, body length and food utilization rate of SD rats. Also, pSPI has a great effect on the growth and antioxidants functions of SD rat.
机译:这项研究的目的是明确加压大豆分离蛋白(pSPI)对SD大鼠身体发育,生长激素和抗氧化剂功能的影响。该方法学取决于选择一百只雄性SD大鼠,将其随机分为5组。每组由20只大鼠组成。将这些组定义为一个空白对照组,三组分别以低,中和高剂量使用pSPI,另一组为天然大豆分离蛋白(nSPI)。低,中和高剂量分别表示为每重量pSPI 0.333 g / kg,1.667 g / kg和3.333 g / kg。天然大豆分离蛋白以每重量3.333 g / kg nSPI表示。在每组中,将取出四只动物以收集血样并分析胰岛素,例如生长因子-I,生长激素,甲状腺刺激激素,甲状腺素和三碘甲状腺素。其他SD大鼠将连续63天进食。测量每只大鼠的体重,体长和食物摄入量。将分析每只大鼠肝脏和血清中的总抗氧化能力,超氧化物歧化酶(SOD),丙二醛和谷胱甘肽过氧化物酶。结果表明,pSPI中等剂量和高剂量组可明显增加SD大鼠的体重,体长和食物利用率。同样,pSPI对SD大鼠的生长和抗氧化功能也有很大影响。

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