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Comparison of image properties in full-field phase X-ray microscopes based on grating interferometry and Zernike's phase contrast optics

机译:基于光栅干涉法和Zernike相位对比光学的全场相位X射线显微镜的图像特性比较

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摘要

A grating interferometer (GI) system has been installed in an X-ray microscope equipped with a Zernike phase contrast (ZPC) system and a Cu rotating anode X-ray source. The GI and ZPC systems are switchable, and their performances of phase information extraction have been compared. The GI system is based on a Lau interferometer consisting of an absorption grating and a pi/2 phase grating, which extracts a magnified phase shift map of a sample via a phase-stepping measurement. The ZPC system generates a phase contrast image by using a phase plate and a corresponding condenser device. The ZPC system and the GI system are compared in terms of detectability of phase objects. By the Fourier analysis of images of a logarithmic ruler pattern, the spatial resolution was found to be identical between the two systems. Although the sensitivity depends on the sample size, the signal-to-noise ratio of polystyrene spheres with a few microns in diameter was used for sensitivity comparison, showing the superior sensitivity of the GI system to that of the ZPC system. The quantitativeness of the GI system with the phase-stepping measurement was also demonstrated over the ZPC system, which generates halo and shade-off artifacts. The GI system exhibits twin image artifacts that need to be resolved for practical applications of the technique. Published by AIP Publishing.
机译:光栅干涉仪(GI)系统已安装在配备Zernike相衬(ZPC)系统和Cu旋转阳极X射线源的X射线显微镜中。 GI和ZPC系统是可切换的,并且已经比较了它们的相位信息提取性能。 GI系统是基于Lau干涉仪的,它由吸收光栅和pi / 2相光栅组成,后者通过相位步进测量来提取样品的放大相移图。 ZPC系统通过使用相位板和相应的冷凝器设备生成相位对比图像。在相位对象的可检测性方面比较了ZPC系统和GI系统。通过对数标尺图案图像的傅立叶分析,发现两个系统之间的空间分辨率相同。尽管灵敏度取决于样本量,但使用直径为几微米的聚苯乙烯球的信噪比进行灵敏度比较,显示了GI系统比ZPC系统具有更高的灵敏度。在ZPC系统上,还证明了具有相位步进测量的GI系统的定量性,该系统会产生光晕和阴影伪影。 GI系统显示双图像伪像,需要对该技术的实际应用进行解析。由AIP Publishing发布。

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  • 来源
    《Applied Physics Letters》 |2018年第6期|063105.1-063105.5|共5页
  • 作者单位

    Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan;

    Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan;

    Carl Zeiss Xray Microscopy Inc, 4385 Hopyard Rd,Suite 100, Pleasanton, CA 94588 USA;

    Carl Zeiss Xray Microscopy Inc, 4385 Hopyard Rd,Suite 100, Pleasanton, CA 94588 USA;

    Carl Zeiss Xray Microscopy Inc, 4385 Hopyard Rd,Suite 100, Pleasanton, CA 94588 USA;

    Carl Zeiss Xray Microscopy Inc, 4385 Hopyard Rd,Suite 100, Pleasanton, CA 94588 USA;

    Carl Zeiss Xray Microscopy Inc, 4385 Hopyard Rd,Suite 100, Pleasanton, CA 94588 USA;

    Carl Zeiss Xray Microscopy Inc, 4385 Hopyard Rd,Suite 100, Pleasanton, CA 94588 USA;

    Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan;

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  • 正文语种 eng
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