Efficacy and Safety of Cetuximab Plus Cisplatin Alone or in Combination With Paclitaxel in Patients With Head and Neck Squamous Cell Carcinoma: A Randomized Trial

机译：单独的Cetuximab加顺铂的功效和安全性或与头部鳞状细胞癌患者的紫杉醇组合：随机试验

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摘要

The aim of this study was to assess the clinical usefulness of cetuximab and cisplatin alone or in combination with paclitaxel as the first-line treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).

机译：本研究的目的是评估西汀昔单抗和顺铂的临床有用性，也可以与紫杉醇组合作为复发或转移头和颈部鳞状细胞癌（HNSCC）的一线治疗。

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期刊名称 Cancer Control : Journal of the Moffitt Cancer Center
作者
Yanqing Zheng; Huiqin Dou; Qingchen Li; Ying Sun; Yanchao Wang; Wendong Zhang;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

机译：香司嗪;顺铂;紫杉醇;头部和颈部鳞状细胞癌;整体生存;

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专利

1. Phase 2, open-label, 1:1 randomized controlled trial exploring the efficacy of EMD 1201081 in combination with cetuximab in second-line cetuximab-na < ve patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) [J] . Ruzsa A., Sen M., Evans M., Investigational new drugs. . 2014,第6期

机译：2期，开放标签，1：1随机对照试验，探讨EMD 1201081联合西妥昔单抗治疗第二线西妥昔单抗-初次复发或转移性头颈部鳞状细胞癌（R / M SCCHN）的患者的疗效）
2. A randomized, phase 2 study of cetuximab plus cisplatin with or without paclitaxel for the first-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck [J] . Bossi P., Miceli R., Locati L. D., Annals of oncology: official journal of the European Society for Medical Oncology . 2017,第11期

机译：一种随机的，相2研究Cetuximab加顺铂，具有或不含紫杉醇，用于患有头部和颈部复发和/或转移性鳞状细胞癌的患者的一线治疗
3. A Phase 2 Trial of Induction nab-Paclitaxel and Cetuximab Given With Cisplatin and 5-Fluorouracil Followed by Concurrent Cisplatin and Radiation for Locally Advanced Squamous Cell Carcinoma of the Head and Neck [J] . Adkins Douglas, Ley Jessica, Trinkaus Kathryn, Cancer: A Journal of the American Cancer Society . 2013,第4期

机译：顺铂和5-氟尿嘧啶给予纳布-紫杉醇和西妥昔单抗诱导，然后同时进行顺铂和放射治疗头颈部局部晚期鳞状细胞癌的第二阶段试验
4. Interstitial photodynamic therapy in combination with Cetuximab for recurrent head and neck squamous cell carcinoma [C] . Nestor Rigual, Ambujakshan Dildeep, Gal Shafirstein Conference on photonic therapeutics and diagnostics IX . 2013

机译：间质性光动力疗法联合西妥昔单抗治疗复发性头颈部鳞状细胞癌
5. GGTI-298 in combination with EGFR inhibitors: Evaluating a novel therapy in head and neck squamous cell carcinomas. [D] . Zahr, Stephanie. 2013

机译：GGTI-298与EGFR抑制剂联合使用：评价头颈部鳞状细胞癌的新疗法。
6. Randomized Phase II Study with Cetuximab in Combination with 5-FU and Cisplatin or Carboplatin Vs. Cetuximab in Combination with Paclitaxel and Carboplatin for Treatment of Patients with Relapsed or Metastatic Squamous Cell Carcinoma of the Head and Neck (CETMET Trial) [O] . Georgios Tsakonas, Lena Specht, Claus Andrup Kristensen, 2020

机译：随机阶段II与西汀昔单抗与5-FU和顺铂或Carboplatin与Cetuximab一起研究。西妥昔单抗与紫杉醇和卡铂联合治疗头部和颈部复发或转移性鳞状细胞癌的患者（Cetmet试验）
7. Efficacy and Safety of Cetuximab Plus Cisplatin Alone or in Combination With Paclitaxel in Patients With Head and Neck Squamous Cell Carcinoma: A Randomized Trial [O] . Yanqing Zheng, Huiqin Dou, Qingchen Li, 2021

机译：单独的Cetuximab加顺铂的功效和安全性，或与头部鳞状细胞癌患者的紫杉醇组合：随机试验

Efficacy and Safety of Cetuximab Plus Cisplatin Alone or in Combination With Paclitaxel in Patients With Head and Neck Squamous Cell Carcinoma: A Randomized Trial

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