Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease

机译：人类恰加斯病疫苗候选者的抗原性和诊断潜力

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

BackgroundChagas disease, caused by Trypanosoma cruzi, is endemic in Latin America and an emerging infectious disease in the US and Europe. We have shown TcG1, TcG2, and TcG4 antigens elicit protective immunity to T. cruzi in mice and dogs. Herein, we investigated antigenicity of the recombinant proteins in humans to determine their potential utility for the development of next generation diagnostics for screening of T. cruzi infection and Chagas disease.

机译：背景由查氏锥虫引起的南美锥虫病在拉丁美洲很流行，在美国和欧洲正在成为一种新兴的传染病。我们已经显示，TcG1，TcG2和TcG4抗原在小鼠和狗中引起对克氏锥虫的保护性免疫。在这里，我们调查了人类中重组蛋白的抗原性，以确定其潜在潜力，可用于开发下一代诊断克氏锥虫感染和南美锥虫病的诊断方法。

著录项

期刊名称 PLoS Neglected Tropical Diseases
作者
Shivali Gupta; Xianxiu Wan; Maria P. Zago; Valena C. Martinez Sellers; Trevor S. Silva; Dadjah Assiah; Monisha Dhiman; Sonia Nuñez; John R. Petersen; Juan C. Vázquez-Chagoyán; Jose G. Estrada-Franco; Nisha Jain Garg;
展开▼
作者单位

展开▼
年(卷),期 2013(7),1
年度 2013
页码 e2018
总页数 10
原文格式 PDF
正文语种
中图分类寄生动物、寄生虫学;医学寄生虫学;
关键词

相似文献

外文文献
中文文献
专利

1. Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease [J] . Shivali Gupta, Xianxiu Wan, Maria P. Zago, PLOS Neglected Tropical Diseases . 2013,第1期

机译：人类恰加斯病疫苗候选者的抗原性和诊断潜力
2. Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease [J] . Seid Christopher A., Jones Kathryn M., Pollet Jeroen, Human vaccines & immunotherapeutics. . 2017,第3期

机译：半胱氨酸诱变改善了生产而不消除重组蛋白质疫苗候选人的抗原性的人噬菌体疾病
3. Cloning, expression, and characterization of TonB2 from Actinobacillus pleuropneumoniae and potential use as an antigenic vaccine candidate and diagnostic marker [J] . Liu Jinlin, Chen Yan, Yuan Fangyan, Canadian Journal of Veterinary Research . 2011,第3期

机译：胸膜肺炎放线杆菌TonB2的克隆，表达和鉴定及其作为抗原疫苗候选物和诊断标记的潜在用途
4. Synthesis and refolding of G20,a potential antigen for human Respiratory Syncytial Virus (hRSV) vaccine [C] . Christine Klinguer-Hamour, Marie-Claire Bussat, Helene Plotnicky-Gilquin, European Peptide Symposium . 2002

机译：G20的合成和重折叠，人类呼吸合胞病毒（HRSV）疫苗的潜在抗原
5. Studies of human rotavirus candidate non-replicating vaccines and innate immunity in a gnotobiotic pig model of human rotavirus disease . [D] . Gonzalez, Ana Maria. 2007

机译：人轮状病毒候选非复制疫苗和人免疫原性免疫的研究
6. Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease [O] . Christopher A. Seid, Kathryn M. Jones, Jeroen Pollet, 2017

机译：半胱氨酸诱变提高了产量却没有消除人类南美锥虫病候选重组蛋白疫苗的抗原性
7. Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease [O] . Gupta, Shivali, Wan, Xianxu, Zago, María Paola, 2016

机译：候选疫苗在人类恰加斯病中的抗原性和诊断潜力
8. Basic Research Effort Toward Development of a Vaccine Against Human Brucellosis;Identification of Protective Brucella Antigens and Their Expression in Vaccinia Virus to Prevent Disease in Animals and Humans [R] . Schurig, G. G. 1997

机译：针对人类布鲁氏菌病疫苗开发的基础研究工作;保护布鲁氏菌抗原的鉴定及其在痘苗病毒中的表达，以预防动物和人类疾病

Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅