Peptide to diagnose immunize against T. Cruzi infection Elisa diagnostic assay to detect specific antibodies to T. Cruzi infection in the blood method of detecting Chagas disease or T. Cruzi infection and vaccine to immunize an individual against Chagas disease

摘要

There is disclosed an antigenic peptide that comprises at least 15 amino acids having the sequence Ala Glu Pro Lys X Ala Glu Pro Lys X Ala Glu Pro Lys X, wherein X is Pro or Ser. This peptide is useful in an ELISA assay to detect antibodies specific to T. cruzi infection and Chagas disease. This peptide is further useful in a vaccine composition for immunizing an individual to prevent Chagas disease upon exposure to T. cruzi.