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PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma

机译：PPARγ依赖性诱导前列腺癌和膀胱癌的生长停滞和凋亡

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BackgroundAlthough PPARγ antagonists have shown considerable pre-clinical efficacy, recent studies suggest PPARγ ligands induce PPARγ-independent effects. There is a need to better define such effects to permit rational utilization of these agents.

机译：背景尽管PPARγ拮抗剂已显示出相当大的临床前功效，但最近的研究表明PPARγ配体可诱导PPARγ依赖性作用。需要更好地定义这种效果以允许合理地利用这些试剂。

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期刊名称 BMC Cancer
作者
Christine L Chaffer; David M Thomas; Erik W Thompson; Elizabeth D Williams;
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年(卷),期 2006(6),-1
年度 2006
页码 53
总页数 13
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma [J] . Christine L Chaffer, David M Thomas, Erik W Thompson, BMC Cancer . 2006,第1期

机译：PPARγ依赖性诱导前列腺癌和膀胱癌的生长停滞和凋亡
2. The ligands of peroxisome proliferator-activated receptor (PPAR) gamma inhibit growth of human esophageal carcinoma cells through induction of apoptosis and cell cycle arrest. [J] . Fujii D, Yoshida K, Tanabe K, Anticancer Research: International Journal of Cancer Research and Treatment . 2004,第3Appa期

机译：过氧化物酶体增殖物激活受体（PPAR）γ的配体通过诱导凋亡和细胞周期停滞来抑制人食道癌细胞的生长。
3. Ethyl acetate fraction from methanol extraction of Vitis thunbergii var. taiwaniana induced G_0/G_1 phase arrest via inhibition of cyclins D and E and induction of apoptosis through caspase-dependent and -independent pathways in human prostate carcinoma DU145 cells [J] . Chia-Hsin Lin, Hsiao-Sung Chan, Hsin-Sheng Tsay, Environmental toxicology . 2018,第1a2期

机译：葡萄藤提取物甲醇提取的乙酸乙酯级分。 taiwaniana通过抑制细胞周期蛋白D和E诱导G_0 / G_1期停滞，并通过胱天蛋白酶依赖性和非依赖性途径诱导人前列腺癌DU145细胞凋亡
4. Induction of G2/M phase arrest and apoptosis by potent antitumor thirty-two-8-oxo-8H-acenaphtho1,2-bpyrrole-9-carbonitrile derivative in human cervix carcinoma cells [C] . rn, rn, rn Asian Pacific Confederation of Chemical Engineering congress . 2008

机译：强效抗肿瘤三十二-8-氧-8H-ac 1,2-b吡咯-9-腈衍生物在人宫颈癌细胞中诱导G2 / M期阻滞和凋亡
5. Mechanism of 3,3'-diindolylmethane-induced cell death in human C33A cervical cancer cells: Induction of endoplasmic reticulum stress, apoptosis and the role of growth-arrest and DNA-damage genes [D] . Han, Jing Y. 2009

机译：3,3'-二吲哚基甲烷诱导的人C33A宫颈癌细胞死亡的机制：内质网应激，细胞凋亡以及生长停滞和DNA损伤基因的作用
6. Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest Apoptosis and Autophagy Induction [O] . Fuguang Zhao, Olesya Vakhrusheva, Sascha D. Markowitsch, 2020

机译：通过细胞周期停滞细胞凋亡和自噬诱导青蒿琥酯损害顺铂抗性膀胱癌细胞的生长
7. PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma [O] . 2006

机译：PPARγ依赖性诱导前列腺癌和膀胱癌的生长停滞和凋亡

PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma

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