Processes to detect and list rare and cancer cells in a mixed cell population, to diagnose early stage cancer in a test patient, to determine the likelihood of cancer recurrence in a previously treated human patient, to distinguish a carcinoma confined to the organ of a carcinoma with metastatic properties, to monitor the situation of remission in a human patient with cancer undergoing treatment of cancer therapy and to increase amounts of circulating epithelial cells in a blood sample, coated magnetic particle, composition,test groups to evaluate a patient sample for the presence of circulating rare cells, for the presence of circulating tumor cells, for the presence of circulating breast cancer cells, for the presence of circulating prostate cancer cells, regarding the presence of circulating colon cancer cells, the presence of circulating bladder cancer cells and to monitor a patient for recurrence of cancer, and, peripheral blood fraction enriched with circulating neoplastic cells

摘要

'' processes to detect and enumerate rare cells in a mixed cell population and cancer to diagnose cancer of early stage in a patient test.To determine the likelihood of recurrence of cancer in a human patient previously treated for cancer.In order to distinguish carcinoma confined to the body of a carcinoma with metastatic properties.To monitor the situation of remission in a human patient with cancer through the treatment of therapy against cancer and for increasing amounts of circulating epithelial cells in a amostRA blood, partu00eccula magnetic coated composition, test kits to measure a sample of patient and the presence of circulating rare cells.As the presence of circulating tumor cells, qiuanto the presence of cells of breast cancer and the presence of circulating prostate cancer cells circulating in the blood.As the presence of circulating cells of colon cancer, and the presence of circulating cancer cells of bladder and to monitor a patient as the recurrence of cancer, and,The fraction of peripheral blood circulating neoplastic cells enriched for '' a highly sensitive test is disclosed.Which combines the enrichment imunomagnu00e9tico with flow analysis and immunocytochemical citomu00e9trico multiple parameter to detect, enumerate and characterize cancer cells in the blood.The test can detect a cell, epithelial or smaller in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry of the order of magnitude of 1 to 2.In addition, the test makes the biological characterization and staging of cancer cells.