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MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro

机译：MicroRNA-145通过在体内和体外靶向AKT3抑制mTOR信号通路的激活以抑制侵袭性垂体腺瘤细胞的增殖和侵袭

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摘要

PurposeThis study was designed to explore how miR-145 regulates the mTOR signaling pathway in invasive pituitary adenoma (IPA) by targeting AKT3.

机译：目的本研究旨在探讨miR-145如何通过靶向AKT3来调节侵袭性垂体腺瘤（IPA）中的mTOR信号通路。

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期刊名称 OncoTargets and therapy
作者
Kai Zhou; Yan-Dong Fan; Peng-Fei Wu; Serick Duysenbi; Zhao-Hai Feng; Guo-Jia Du; Ting-Rong Zhang;
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作者单位

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年(卷),期 2017(10),-1
年度 2017
页码 1625–1635
总页数 11
原文格式 PDF
正文语种
中图分类应用微生物学 ; 肿瘤学 ;
关键词
invasive pituitary adenoma microRNA-145 mTOR signaling pathway proliferation invasion AKT3;

机译：侵袭性垂体腺瘤;microRNA-145;mTOR信号通路;增殖;侵袭;AKT3;

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专利

1. MicroRNA-145 Inhibits the Activation of the mTOR Signaling Pathway to Suppress the Proliferation and Invasion of Invasive Pituitary Adenoma Cells by Targeting AKT3 in vivo and in vitro [Retraction] [J] . Zhou K, Fan Y, Wu P, OncoTargets and therapy . 2020 ,第2期

机译：MicroRNA-145抑制MTOR信号传导途径的激活，抑制通过体内和体外靶向侵入性垂体腺瘤细胞的增殖和侵袭[缩回]
2. MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro [J] . Kai Zhou, Yan-Dong Fan, Peng-Fei Wu, OncoTargets and therapy . 2017 ,第6期

机译：MicroRNA-145通过在体内和体外靶向AKT3来抑制mTOR信号通路的激活以抑制侵袭性垂体腺瘤细胞的增殖和侵袭
3. Hesperetin inhibits Eca-109 cell proliferation and invasion by suppressing the PI3K/AKT signaling pathway and synergistically enhances the anti-tumor effect of 5-fluorouracil on esophageal cancer in vitro and in vivo [J] . Wu Dandan, Li Jiao, Hu Xue, RSC Advances . 2018 ,第43期

机译：默特林抑制PI3K / AKT信号通路抑制ECA-109细胞增殖和侵袭，并协同增强体外和体内食管癌5-氟尿嘧啶的抗肿瘤作用
4. Expression of Matrix Metalloproteinases and Their Inhibitors in Invasive Pituitary Adenomas [C] . W. Liebert, J. Szymas, R. Wasko, European Congress of Neurosurgery . 2003

机译：侵袭性垂体腺瘤中基质金属蛋白酶及其抑制剂的表达
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. MicroRNA-145 Inhibits the Activation of the mTOR Signaling Pathway to Suppress the Proliferation and Invasion of Invasive Pituitary Adenoma Cells by Targeting AKT3 in vivo and in vitro Retraction [O] . 2020

机译：MicroRNA-145抑制MTOR信号传导途径的激活抑制通过体内和体外靶向侵入性垂体腺瘤细胞的增殖和侵袭缩回
7. >MicroRNA-145 Inhibits the Activation of the mTOR Signaling Pathway to Suppress the Proliferation and Invasion of Invasive Pituitary Adenoma Cells by Targeting AKT3 in vivo and in vitro Retraction [O] . Kai Zhou, Yan-Dong Fan, Peng-Fei Wu, 2020

机译：> microRNA-145抑制MTOR信号传导途径的激活，抑制通过体内和体外靶向侵入性垂体腺瘤细胞的增殖和侵袭，并在体外收缩

MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro

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