compound intended to stimulate the il-15r beta / gamma signaling pathway, nucleic acid encoding a compound, vector, host cell, adjuvant for immunotherapeutic composition, compositions, drug, in vitro induction process and / or stimulation of proliferation and / or beta-gamma-positive il-15r cell activation, in vitro process of producing activated te / or nk cells and use of at least one polypeptide

摘要

COMPOSITE AIMED AT STIMULATING THE SIGNALING ROUTE OF IL-15R BETA / GAMA, NUCLEIC ACID THAT CODES FOR A COMPOUND, VECTOR, HOST CELL, ADJUVANT FOR IMMUNE THERAPY AND COMPOSITION, PROTECTION, PROCEDURES, PROCEEDINGS / OR ACTIVATION OF IL-15R BETA / RANGE-POSITIVE CELLS, IN VITRO PROCESS OF ACTIVATED TE / OR NK CELLS AND USE OF AT LEAST ONE POLYPEPTIDE The present invention relates to stimulating the IL-15R beta / signaling pathway gamma, in order to induce and / or stimulate the activation and / or proliferation of IL-15R beta / gamma-positive cells, such as NK and / or T cells. Suitable compounds include compounds that comprise at least one IL-binding entity -15R beta / gamma, directly or indirectly linked by covalence to at least one polypeptide that contains the sushi domain of the IL-15R alpha extracellular region.