目的：研究康柏西普联合曲安奈德玻璃体内注射治疗黄斑水肿疗效。方法经光学相干断层扫描和眼底血管荧光造影检查确诊糖尿病黄斑水肿患者45例，共85只眼，对照组采用单纯曲安奈德玻璃体内注射治疗，治疗组采用康柏西普联合曲安奈德治疗，分别对治疗前和治疗后1、3个月患者光学相干断层扫描、矫正视力和眼压等进行观察，用SPASS 17.0软件进行统计学分析。结果2种方法治疗3个月，患者视力都有所提高，且2种药物联合使用对光学相干断层扫描和矫正视力的改善效果更为显著。结论康柏西普联合曲安奈德玻璃体内注射是治疗糖尿病黄斑水肿的有效方法，可以提高治疗的安全性和有效性。%Objective This study is to explore the curative effect of conbercept combined with triamcinolone acetonide to treat retinal veinobstruction caused by macular edema. Methods We used optical coherence tomography ( OCT) and fundus fluorescein angiography ( FFA) to diag-nose 45 patients with diabetic macular edema, a total of 85 eyes included. Patients in A groups were simply treated with triamcinolone acetonide treatment, while in B groups were treated by conbercept combined with triamcinolone acetonide. OCT and corrected visual acuity, intraocular pressure and other adverse reactions were observed before and after treatment for 1 months and 3 months respec-tively. The statistical analysis was performed with SPSS 17. 0. Results Compared with pretherapy, the patient’s visual acuity had largely improved for 3 months after treatment. OCT and corrected vi-sual acuity improvement effect were more significant in group of drugs combination. Conclusion Conbercept combined with intravitreal injection of triamcinolone acetonide is an effective method for diabetic macular edema of therapy, which can improve the safety and efficacy of treatment.
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