目的 研究西洋参根中多糖对肝脏恶性肿瘤的抑制作用,探索西洋参多糖对肝脏肿瘤的治疗作用.方法 我们建立了BABL/C小鼠肝癌模型,用多糖干扰小鼠肝癌的发生发展,观测小鼠肝脏肿瘤以及脾脏的变化,评估小鼠的抗肝癌效果和西洋参多糖的免疫调节效果.结果 随着多糖用量的加大,小鼠肿瘤重量明显减小,肿瘤抑制率明显增加(P＜0.05),小鼠免疫调节越显著.结论 可见西洋参多糖对肿瘤的抑制作用明显,可以为肿瘤免疫治疗提供一条新途径.%Objective For the research suppression glucogalactan from the roots of Panax quinquefolium to hepatocellular carcinoma, we study the treatment effect of glucogalactan from Panax Quinquefolium( PPQ )to hepatocellular carcinoma. Methods We established BABL/C mouse model of hepatocellular carcinoma; used PPQ interference mouse hepatocellular carcinoma development; observed the variation of mouse hepatocellular carcinoma and spleen and estimated effect of anti - hepatocellular carcinoma and PPQ immunoregulation. Results With the increasing of PPQ dosage,mice tumor weight decrease obviously,and tumor inhibitory rate increase obvi-ously( P < 0. 05 ). Mice immunoregulatory effect is remarkable. Conclusion So, PPQ to the tumor inhibition is obvious. It may provide a new way for tumor immunotherapy.
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