降钙素原水平检测对鉴别重症监护病房血流感染患者菌种的作用

摘要

目的：探讨PCT水平对鉴别重症监护病房血流感染患者菌种的价值。方法：选择2011年3月-2014年1月本院ICU患者131例作为研究对象，按照其菌种将其分为G-组、G+组及真菌组，比较各组PCT水平差异，并根据其ROC曲线判断血清PCT的诊断性能。结果：三组血清PCT中位数水平差异具有统计学意义（P<0.05）；血清PCT水平对G-菌与G+菌及真菌所致的血流感染鉴别诊断性能较高。结论：血清PCT水平对于鉴别G-菌与G+菌或真菌引起的血流感染有一定的临床鉴别价值，但是对于G+菌与真菌引起的感染鉴别意义尚不明确。%Objective:To investigate the value of calcitonin original level in identifying bacterial bloodstream infections of patients in intensive care unit. Method:131 patients in ICU of our hospital from March 2011 to January 2014 were selected as the objects.They were divided into group G-,group G+and group fungi according to different strains.Differences in PCT levels were compared among the three groups and diagnostic performance of serum PCT was determined according to its ROC curve. Result:Differences in median serum PCT levels of the three groups were statistically significant.Serum PCT level has a higher diagnostic capacity in differentiating bloodstream infections caused by G-bacteria and G+bacteria or fungi.Conclusion:Serum PCT level plays a certain role in differentiating bloodstream infections caused by G-bacteria and G+bacteria or fungi,but it plays an uncertain role in differentiating infections caused by G+bacteria and fungi.