心身学说视角下对代谢综合征合并抑郁障碍病机探讨

摘要

[Objective]This paper will pitch-in TCM psychosomatic theory(from "Huangdi Neijing"),exploring the disorders of depression with the metabolic syndrome and pathogenesis of traditional Chinese medicine,so as to provide effective ideas for the treatment of depression with metabolic syndrome.[Methods]:Through expansion on traditional chinese medicine's basic understanding of depression with metabolic syndrome,utilizing basic TCM viscera-state theory, from the causes of this disease,key factors,pathogenesis transformation three aspects to discuss the pathogenesis of the disease. [Results]By discussing the heart,liver,spleen function of zang-fu organs and their mutual relations in the role and impact of the disease development process, this paper thinks of the nature of disease as asthenia in origin and asthenia in superficiality,which locates in spleen,has association with heart and liver, phlegm, qi and blood stasis is the disease of pathological product of pathological factors to promote the development of the disease.Kidney would be involved in it with long course of disease.The therapy could focus on tonifying spleen,nourishing heart and soothing liver,with methods of promoting the circulation of qi,removing blood stasis and reducing phlegm,meanwhile looking out to protect kidney.[Conclusion]Disorder of depression and pathogenesis of TCM of metabolic syndrome,to guide the clinical treatment of the disease and the theory of traditional Chinese medicine development has practical significance.%[目的]从《黄帝内经》心身学说的视角切入,探讨代谢综合征合并抑郁障碍的中医病机,从而为该病的临床中医论治提供理论思路.[方法]从心身学说情志因素入手,运用中医藏象基础理论,从发病根源、关键因素、病机转化三方面展开对本病的病机探讨.[结果]通过探讨心、肝、脾脏腑功能及其相互关系在本病发生发展过程中的作用及影响,认为代谢综合征合并抑郁障碍病性总属本虚标实,病位在脾,与心、肝密切相关.痰、气、瘀既是本病的病理产物,也是促进本病发展的病理因素.病程日久,累及于肾.治疗当以健脾益心疏肝为主,辅以行气祛瘀化痰之法,用药时兼顾固益肾气.[结论]代谢综合征合并抑郁障碍的中医病机探讨,对指导该病的临床治疗及中医理论发展均有丰富的现实意义.